Trial · NCT00044655
Switching Medication to Treat Schizophrenia
NCT00044655, Phase 4, Completed, Icahn School of Medicine at Mount Sinai; results first posted 2013-12-05
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Switching Medication to Treat Schizophrenia. Trials, record NCT00044655. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00044655
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Switching Medication to Treat Schizophrenia
- NCT number
- NCT00044655
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 219 participants, actual
- Lead sponsor
- Icahn School of Medicine at Mount Sinai
- Conditions
- Schizophrenia
- Interventions
- Risperidone, Olanzapine, Ziprasidone, Quetiapine, Aripiprazole
- First posted
- 2002-09-05
- Last updated
- 2026-05-15
- Results first posted
- 2013-12-05
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number Who Discontinued Medication Within First 6 Study Months | Measured at Six Months | |
| Secondary | Number of Participants Hospitalized | during first 6 months | Number of participants hospitalized for psychiatric reasons |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number Who Discontinued Medication Within First 6 Study Months | Measured at Six Months | intent to treat samples for 2 substudies: injectable to injectable and polypharmacy to monotherapy | participants | NUMBER |
| SECONDARY | Psychiatric Symptoms, Hospitalization, and Medication Side Effects | Measured at Year 1 |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number Who Discontinued Medication Within First 6 Study Months | Stay | 11 | participants | ||
| Number Who Discontinued Medication Within First 6 Study Months | Switch | 23 | participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Stay | 102 | |
| Overall Study | STARTED | Switch | 117 | |
| Overall Study | COMPLETED | Stay | 82 | |
| Overall Study | COMPLETED | Switch | 79 | |
| Overall Study | NOT COMPLETED | Stay | 20 | |
| Overall Study | NOT COMPLETED | Switch | 38 |
Source ClinicalTrials.gov
Adverse events4
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Psychiatric Hospitalization | Psychiatric disorders | Stay | 0 | 102 | 0 |
| serious | Psychiatric Hospitalization | Psychiatric disorders | Switch | 1 | 117 | 1 |
| serious | Death | Cardiac disorders | Stay | 0 | 102 | 0 |
| serious | Death | Cardiac disorders | Switch | 1 | 117 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Stay | ||
| Total, all-cause mortality | Switch | ||
| Total, other adverse events | Stay | 0 | 102 |
| Total, other adverse events | Switch | 0 | 117 |
| Total, serious adverse events | Stay | 0 | 102 |
| Total, serious adverse events | Switch | 2 | 117 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01MH059312 | EFFECTIVENESS OF SWITCHING ANTIPSYCHOTIC MEDICATIONS | ESSOCK, SUSAN M | MOUNT SINAI SCHOOL OF MEDICINE OF NYU | NATIONAL INSTITUTE OF MENTAL HEALTH | 2001 to 2003 |
Source NIH RePORTER
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Stay vs Switch: Number Who Discontinued Medication Within First 6 Study Months | Trial comparisons |
| Stay vs Switch: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00044655
GET https://conductscience.org/api/trials/v1/NCT00044655/registered