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Trial · NCT00075998

The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF)

NCT00075998, Phase 3, Terminated, InterMune

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF). Trials, record NCT00075998. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00075998

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
The INSPIRE Trial: A Study of Interferon Gamma-1b for Idiopathic Pulmonary Fibrosis (IPF)
NCT number
NCT00075998
Status
Terminated
Phases
Phase 3
Enrollment
826 participants, actual
Lead sponsor
InterMune
Conditions
Idiopathic Pulmonary Fibrosis, Lung Disease, Pulmonary Fibrosis
Interventions
Interferon gamma-1b ("Actimmune")
First posted
2004-01-14
Last updated
2009-07-02

Source ClinicalTrials.gov

Registered outcomes4

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimarySurvival time from randomization to treatment completion visit, or, end of treatment period, or, last known vital status.3.5 years
SecondaryLung transplant-free survival time (ongoing assessment up to end of study).3.5 years
SecondaryTotal number of days without hospitalization resulting from respiratory admission diagnosis (ongoing assessment up to end of study).3.5 years
SecondaryChanges from baseline measurement to week 96 measurement in the following (measured every 24 weeks): 6-minute walk test, shortness of breath96 weeks

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers7

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
19570573DERIVEDPubMed
24311766DERIVEDPubMed
28657784DERIVEDPubMed
31047956DERIVEDPubMed
33434107DERIVEDPubMed
35688625DERIVEDPubMed
38238788DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00075998

GET https://conductscience.org/api/trials/v1/NCT00075998/registered