Trial · NCT00084929
The National CT Colonography Trial
NCT00084929, Not applicable, Completed, American College of Radiology Imaging Network; results first posted 2020-11-16
3 sourcestrials-2026-11-12-0.4.0
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ConductScience Library. The National CT Colonography Trial. Trials, record NCT00084929. Release trials-2026-11-12-0.4.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00084929
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Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The National CT Colonography Trial
- NCT number
- NCT00084929
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 2,600 participants, actual
- Lead sponsor
- American College of Radiology Imaging Network
- Conditions
- Colorectal Cancer
- Interventions
- CT Colonography
- First posted
- 2004-06-11
- Last updated
- 2020-12-22
- Results first posted
- 2020-11-16
Source ClinicalTrials.gov
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Participants With Advanced Adenomas (>=10mm) as Determined by Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=10mm (as measured at pathology) RS-: No Advanced adenomas \>=10mm found by colonoscopy (as measured at pathology) |
| Primary | Number of Participants With Advanced Adenomas (>=9mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=9mm (as measured at pathology) RS-: No Advanced adenomas \>=9mm found by colonoscopy (as measured at pathology) |
| Primary | Number of Participants With Advanced Adenomas (>=8mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=8mm (as measured at pathology) RS-: No Advanced adenomas \>=8mm found by colonoscopy (as measured at pathology) |
| Primary | Number of Participants With Advanced Adenomas (>=7mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=7mm (as measured at pathology) RS-: No Advanced adenomas \>=7mm found by colonoscopy (as measured at pathology) |
| Primary | Number of Participants With Advanced Adenomas (>=6mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=6mm (as measured at pathology) RS-: No Advanced adenomas \>=16mm found by colonoscopy (as measured at pathology) |
| Primary | Number of Participants With Advanced Adenomas (>=5mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard (RS) for determining the existence of advanced adenomas. RS+: Colonoscopy found at least 1 Advanced adenomas \>=5mm (as measured at pathology) RS-: No Advanced adenomas \>=5mm found by colonoscopy (as measured at pathology) |
| Secondary | Number of Advanced Adenoma or Cancer Lesions (>=10mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard for determining the existence of advanced adenomas. CTC lesions needed to be within 2 segments and 50% size of the lesions removed via colonoscopy to be considered "detected" |
| Secondary | Number of Advanced Adenoma or Cancer Lesions (>=9mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard for determining the existence of advanced adenomas. CTC lesions needed to be within 2 segments and 50% size of the lesions removed via colonoscopy to be considered "detected" |
| Secondary | Number of Advanced Adenoma or Cancer Lesions (>=8mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard for determining the existence of advanced adenomas. CTC lesions needed to be within 2 segments and 50% size of the lesions removed via colonoscopy to be considered "detected" |
| Secondary | Number of Advanced Adenoma or Cancer Lesions (>=7mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | Pathology results from Colonoscopy performed up to 30 days after a CTC examination were used as the reference standard for determining the existence of advanced adenomas. CTC lesions needed to be within 2 segments and 50% size of the lesions removed via colonoscopy to be considered "detected" |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 registered outcomesOutcomes13
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Participants With Advanced Adenomas (>=10mm) as Determined by Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| PRIMARY | Number of Participants With Advanced Adenomas (>=9mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| PRIMARY | Number of Participants With Advanced Adenomas (>=8mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| PRIMARY | Number of Participants With Advanced Adenomas (>=7mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| PRIMARY | Number of Participants With Advanced Adenomas (>=6mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| PRIMARY | Number of Participants With Advanced Adenomas (>=5mm) Detected by CT Colonoscopy (Per Patient) | within 30 days | Participants | COUNT_OF_PARTICIPANTS | |
| SECONDARY | Number of Advanced Adenoma or Cancer Lesions (>=10mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | lesions | COUNT_OF_UNITS | |
| SECONDARY | Number of Advanced Adenoma or Cancer Lesions (>=9mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | lesions | COUNT_OF_UNITS | |
| SECONDARY | Number of Advanced Adenoma or Cancer Lesions (>=8mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | lesions | COUNT_OF_UNITS | |
| SECONDARY | Number of Advanced Adenoma or Cancer Lesions (>=7mm) Detected by CT Colonoscopy (Per Lesion) | within 30 days | lesions | COUNT_OF_UNITS |
1 to 10 of 13Source ClinicalTrials.gov
See all 13 outcomesResults by group26
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Participants With Advanced Adenomas (>=10mm) as Determined by Colonoscopy (Per Patient) | CT Colonography | RS+ | 109 | Participants | |
| Number of Participants With Advanced Adenomas (>=10mm) as Determined by Colonoscopy (Per Patient) | CT Colonography | RS- | 2422 | Participants | |
| Number of Participants With Advanced Adenomas (>=9mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS+: Advanced Adenoma >=9mm | 120 | Participants | |
| Number of Participants With Advanced Adenomas (>=9mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS-: Not Advanced Adenoma >=9mm | 2411 | Participants | |
| Number of Participants With Advanced Adenomas (>=8mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS+: Advanced Adenoma >=8mm | 154 | Participants | |
| Number of Participants With Advanced Adenomas (>=8mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS-: Not Advanced Adenoma >=8mm | 2377 | Participants | |
| Number of Participants With Advanced Adenomas (>=7mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS+: Advanced Adenoma >=7mm | 174 | Participants | |
| Number of Participants With Advanced Adenomas (>=7mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS-: Not Advanced Adenoma >=7mm | 2357 | Participants | |
| Number of Participants With Advanced Adenomas (>=6mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS+: Advanced Adenoma >=6mm | 210 | Participants | |
| Number of Participants With Advanced Adenomas (>=6mm) Detected by CT Colonoscopy (Per Patient) | CT Colonography | RS-: Not Advanced Adenoma >=6mm | 2321 | Participants |
1 to 10 of 26Source ClinicalTrials.gov
See all 26 results by groupParticipant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | CT Colonography | 2,600 | |
| Overall Study | COMPLETED | CT Colonography | 2,531 | |
| Overall Study | NOT COMPLETED | CT Colonography | 69 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | hemorrhage with surgery | Gastrointestinal disorders | CT Colonography | 0 | 2,600 | 0 |
| serious | hemorrhage with surgery | Gastrointestinal disorders | Colonoscopy | 1 | 2,600 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | CT Colonography | 0 | 2,600 |
| Total, all-cause mortality | Colonoscopy | 0 | 2,600 |
| Total, other adverse events | CT Colonography | 0 | 2,600 |
| Total, other adverse events | Colonoscopy | 0 | 2,600 |
| Total, serious adverse events | CT Colonography | 0 | 2,600 |
| Total, serious adverse events | Colonoscopy | 1 | 2,600 |
Source ClinicalTrials.gov
Papers5
The papers the trial lists on ClinicalTrials.gov.
Grants2
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|---|---|---|---|---|---|
| U01CA079778 | Biostatistics Data Management Center for ACRIN | GATSONIS, CONSTANTINE A. | BROWN UNIVERSITY | NATIONAL CANCER INSTITUTE | 1999 to 2011 | NIH RePORTER |
| U01CA080098 | American College of Radiology Imaging Network | SCHNALL, MITCHELL D. | AMERICAN COLLEGE OF RADIOLOGY | NATIONAL CANCER INSTITUTE | 1999 to 2011 | NIH RePORTER |
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| CT Colonography vs Colonoscopy: deaths from any cause | Trial comparisons |
| CT Colonography vs Colonoscopy: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Source
- Release
- trials-2026-11-12-0.4.0
- Release manifest SHA-256
- 0f4a8d8c48aee2a7573ae0fa94ecbeab70c1adbe449bbc95c424bc7d3e97b9d4
- Registry capture
- 2026-11-12
- Results copy, AACT
- 2026-03-23
- NIH clinical studies file
- 2026-11-13
Source ClinicalTrials.gov
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNone stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00084929
GET https://conductscience.org/api/trials/v1/NCT00084929/results?page=2