Trial · NCT00116857
Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors
NCT00116857, Phase 3, Completed, Washington University School of Medicine; results first posted 2012-09-12
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors. Trials, record NCT00116857. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00116857
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Omega-3 Fatty Acids to Improve Depression and Reduce Cardiovascular Risk Factors
- NCT number
- NCT00116857
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 122 participants, actual
- Lead sponsor
- Washington University School of Medicine
- Conditions
- Cardiovascular Diseases, Depression, Heart Diseases, Myocardial Infarction, Angina, Unstable
- Interventions
- Sertraline/omega-3, Sertraline/Corn Oil
- First posted
- 2005-07-01
- Last updated
- 2012-09-12
- Results first posted
- 2012-09-12
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Beck Depression Inventory-II | Measured at Baseline and 10 weeks | Beck Depression Inventory-II scores on a scale of 0 to 63, minimum score equals 0 maximum score equals 63. Higher value represents a worse outcome. Baseline scores are compared to scores after treatment. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Beck Depression Inventory-II | Measured at Baseline and 10 weeks | units on a scale | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Beck Depression Inventory-II | Sertraline Plus Omega-3 Supplement | 16.1 | Standard Deviation 10.2 | units on a scale | |
| Beck Depression Inventory-II | Sertraline/Corn Oil | 14.8 | Standard Deviation 9.7 | units on a scale |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Sertraline Plus Omega-3 Supplement | 62 | |
| Overall Study | STARTED | Sertraline/Corn Oil | 60 | |
| Overall Study | COMPLETED | Sertraline Plus Omega-3 Supplement | 59 | |
| Overall Study | COMPLETED | Sertraline/Corn Oil | 56 | |
| Overall Study | NOT COMPLETED | Sertraline Plus Omega-3 Supplement | 3 | |
| Overall Study | NOT COMPLETED | Sertraline/Corn Oil | 4 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Sertraline Plus Omega-3 Supplement | ||
| Total, all-cause mortality | Sertraline/Corn Oil | ||
| Total, other adverse events | Sertraline Plus Omega-3 Supplement | 0 | 62 |
| Total, other adverse events | Sertraline/Corn Oil | 0 | 60 |
| Total, serious adverse events | Sertraline Plus Omega-3 Supplement | 0 | 62 |
| Total, serious adverse events | Sertraline/Corn Oil | 0 | 60 |
Source ClinicalTrials.gov
Papers4
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01HL076808 | Omega-3 for Depression and Other Cardiac Risk Factors | CARNEY, ROBERT M | WASHINGTON UNIVERSITY | NATIONAL HEART, LUNG, AND BLOOD INSTITUTE | 2005 to 2008 |
Source NIH RePORTER
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Sertraline Plus Omega-3 Supplement vs Sertraline/Corn Oil: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00116857
GET https://conductscience.org/api/trials/v1/NCT00116857/registered