Trial · NCT00147264
Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
NCT00147264, Phase 3, Completed, McMaster University
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial. Trials, record NCT00147264. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00147264
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Telmisartan-Induced Reduction in Intra-Myocellular Lipids Trial
- NCT number
- NCT00147264
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 120 participants
- Lead sponsor
- McMaster University
- Conditions
- Metabolic Syndrome X
- Interventions
- Telmisartan (Micardis®) vs. Placebo, Low-Glycemic Index Diet vs. Control Diet
- First posted
- 2005-09-07
- Last updated
- 2016-12-14
Source ClinicalTrials.gov
Registered outcomes19
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | (for both interventions): change in IMCL content in the soleus muscle as assessed by 1H-MRI Spectroscopy at baseline and 6 months | ||
| Secondary | Change in intra-hepatocellular lipid storage as assessed by 1H-MRI Spectroscopy | ||
| Secondary | Change in insulin sensitivity as determined by HOMA index | ||
| Secondary | Reversal of IFG to normal fasting glucose in participants with IFG | ||
| Secondary | Change in 72-hour subcutaneous glucose profile | ||
| Secondary | Change in fasting lipid profile (free fatty acids, triglyceride, total cholesterol, low-density lipoprotein (LDL) and high-density lipoprotein (HDL) cholesterol) | ||
| Secondary | Change in serum/plasma levels of inflammatory markers (C-reactive protein, adiponectin, tumor necrosis factor a, interleukin 6, leptin, adhesion molecules, plasminogen-activation inhibitor-1, t-PA, global test of fibrinolysis, fibrinogen, homocysteine, | ||
| Secondary | Change in beta-cell function as assessed by the Insulin Secretion Index | ||
| Secondary | Other efficacy parameters of the AT1 blockade and LGI diet are: | ||
| Secondary | Change in waist circumference |
1 to 10 of 19Source ClinicalTrials.gov
See all 19 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00147264
GET https://conductscience.org/api/trials/v1/NCT00147264/registered