Trial · NCT00179465
Treating Schizophrenia by Correcting Abnormal Brain Development
NCT00179465, Phase 3, Active not recruiting, Beth Israel Deaconess Medical Center
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Treating Schizophrenia by Correcting Abnormal Brain Development. Trials, record NCT00179465. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00179465
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Treating Schizophrenia by Correcting Abnormal Brain Development
- NCT number
- NCT00179465
- Status
- Active not recruiting
- Phases
- Phase 3
- Enrollment
- 36 participants, estimated
- Lead sponsor
- Beth Israel Deaconess Medical Center
- Conditions
- Schizophrenia
- Interventions
- Tiagabine, Placebo
- First posted
- 2005-09-16
- Last updated
- 2025-01-27
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Neurocognitive Functions-Working Memory | Working memory will be assessed at baseline and at 6-month time point to see if working memory changes after 6 months compared to baseline measurement | Working memory will be assessed using the n-back working memory test |
| Primary | Neurocognitive Functions-Executive Function | Executive function will be assessed at baseline and at 6-month time point to see if executive function changes after 6 months compared to baseline measure | Executive function, which is a complex form of working memory, will be assessed using the MATRICS (Measurement and Treatment Research to Improve Cognition in Schizophrenia) battery |
| Secondary | Clinical symptoms | Symptoms will be assessed at baseline and at 6-month time point to see if symptoms change after 6 months compared to baseline measures | Positive and negative symptoms will be quantified using PANSS (positive and negative symptom scale) |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests2
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as | Source |
|---|---|---|
| 1-Back Task | Primary outcome | ConductCognition |
| 2-Back Task | Primary outcome | ConductCognition |
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00179465
GET https://conductscience.org/api/trials/v1/NCT00179465/registered