Trial · NCT00186069
Magnesium Sulfate vs Placebo for Placental Abruption
NCT00186069, Not applicable, Completed, Stanford University; results first posted 2017-04-20
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Magnesium Sulfate vs Placebo for Placental Abruption. Trials, record NCT00186069. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00186069
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Magnesium Sulfate vs Placebo for Placental Abruption
- NCT number
- NCT00186069
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 30 participants, actual
- Lead sponsor
- Stanford University
- Conditions
- Abruptio Placentae
- Interventions
- Magnesium Sulfate, Normal Saline
- First posted
- 2005-09-16
- Last updated
- 2018-01-02
- Results first posted
- 2017-04-20
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours | 48 hours after the randomization | The primary outcome was the proportion of women undelivered at 48 hours with resolution of vaginal bleeding and uterine contractions. |
| Secondary | Gestational Age at Delivery (Weeks) | Time of delivery | Median gestational age at delivery (in full weeks) |
| Secondary | Neonatal Apgar Score at 5 Minutes | At 5 minutes after birth | The median Apgar score at 5 minutes. Apgar score scale is from 0 to 10 with score 0 expressing the worst neonatal status and score 10 the best status. |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours | 48 hours after the randomization | participants | NUMBER | |
| SECONDARY | Gestational Age at Delivery (Weeks) | Time of delivery | weeks of gestation | MEDIAN | |
| SECONDARY | Neonatal Apgar Score at 5 Minutes | At 5 minutes after birth | Apgar score | MEDIAN |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours | Magnesium Sulfate | 12 | participants | ||
| Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours | Normal Saline | 10 | participants | ||
| Gestational Age at Delivery (Weeks) | Magnesium Sulfate | 36 | Full Range 32 to 38 | weeks of gestation | |
| Gestational Age at Delivery (Weeks) | Normal Saline | 38 | Full Range 33 to 39 | weeks of gestation | |
| Neonatal Apgar Score at 5 Minutes | Magnesium Sulfate | 9 | Full Range 9 to 9 | Apgar score | |
| Neonatal Apgar Score at 5 Minutes | Normal Saline | 9 | Full Range 9 to 9 | Apgar score |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Magnesium Sulfate | 15 | |
| Overall Study | STARTED | Normal Saline | 15 | |
| Overall Study | COMPLETED | Magnesium Sulfate | 15 | |
| Overall Study | COMPLETED | Normal Saline | 15 | |
| Overall Study | NOT COMPLETED | Magnesium Sulfate | 0 | |
| Overall Study | NOT COMPLETED | Normal Saline | 0 |
Source ClinicalTrials.gov
Adverse events8
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Lethargy | Nervous system disorders | Magnesium Sulfate | 0 | 15 | |
| other | Lethargy | Nervous system disorders | Normal Saline | 1 | 15 | |
| other | Headache | Nervous system disorders | Magnesium Sulfate | 1 | 15 | |
| other | Headache | Nervous system disorders | Normal Saline | 0 | 15 | |
| other | Flushing | Skin and subcutaneous tissue disorders | Magnesium Sulfate | 0 | 15 | |
| other | Flushing | Skin and subcutaneous tissue disorders | Normal Saline | 2 | 15 | |
| other | Dizziness | Nervous system disorders | Magnesium Sulfate | 1 | 15 | |
| other | Dizziness | Nervous system disorders | Normal Saline | 0 | 15 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Magnesium Sulfate | ||
| Total, all-cause mortality | Normal Saline | ||
| Total, other adverse events | Magnesium Sulfate | 2 | 15 |
| Total, other adverse events | Normal Saline | 3 | 15 |
| Total, serious adverse events | Magnesium Sulfate | 0 | 15 |
| Total, serious adverse events | Normal Saline | 0 | 15 |
Source ClinicalTrials.gov
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 26871905 | DERIVED |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Magnesium Sulfate vs Normal Saline: Undelivered With Resolution of Vaginal Bleeding and Contractions in First 48 Hours | Trial comparisons |
| Magnesium Sulfate vs Normal Saline: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00186069
GET https://conductscience.org/api/trials/v1/NCT00186069/registered