Trial · NCT00194532

Cefpodoxime vs Ciprofloxacin for Acute Cystitis

NCT00194532, Not applicable, Completed, University of Washington; results first posted 2011-04-28

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Cefpodoxime vs Ciprofloxacin for Acute Cystitis. Trials, record NCT00194532. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00194532

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Cefpodoxime vs Ciprofloxacin for Acute Cystitis
NCT number: NCT00194532
Status: Completed
Phases: Not applicable
Enrollment: 300 participants, actual
Lead sponsor: University of Washington
Conditions: Urinary Tract Infection
Interventions: Cefpodoxime, Ciprofloxacin
First posted: 2005-09-19
Last updated: 2014-06-10
Results first posted: 2011-04-28

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Clinical Cure	28-30 days post therapy	Participants with clinical cure, i.e. free of urinary tract symptoms and requiring no further antibiotic treatment, to assess the efficacy of a 3-day regimen of cefpodoxime compared to ciprofloxacin
Secondary	Microbiologic Cure	1-15 days post therapy	Elimination or decrease of causative uropathogen(s) in the mid-stream urine culture at follow-up

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Clinical Cure	28-30 days post therapy	modified ITT	participants	NUMBER
SECONDARY	Microbiologic Cure	1-15 days post therapy	Per protocol. Participants were eligible for analysis if they had an enrollment urine containing uropathogens and a urine specimen taken at follow-up.	participants	NUMBER

Source ClinicalTrials.gov

Results by group8

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Units
Clinical Cure	Ciprofloxacin	Cure	140	participants
Clinical Cure	Cefpodoxime	Cure	123	participants
Clinical Cure	Ciprofloxacin	Not cure	10	participants
Clinical Cure	Cefpodoxime	Not cure	27	participants
Microbiologic Cure	Ciprofloxacin	Cure	123	participants
Microbiologic Cure	Cefpodoxime	Cure	104	participants
Microbiologic Cure	Ciprofloxacin	Not cure	5	participants
Microbiologic Cure	Cefpodoxime	Not cure	25	participants

Source ClinicalTrials.gov

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Ciprofloxacin	150
Overall Study	STARTED	Cefpodoxime	150
Overall Study	COMPLETED	Ciprofloxacin	150
Overall Study	COMPLETED	Cefpodoxime	150
Overall Study	NOT COMPLETED	Ciprofloxacin	0
Overall Study	NOT COMPLETED	Cefpodoxime	0

Source ClinicalTrials.gov

Adverse events14

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	gastrointestinal(GI) side effects	Gastrointestinal disorders	Ciprofloxacin	23	137	30
other	gastrointestinal(GI) side effects	Gastrointestinal disorders	Cefpodoxime	21	137	26
other	central nervous system (CNS) side effect	Nervous system disorders	Ciprofloxacin	17	137	18
other	central nervous system (CNS) side effect	Nervous system disorders	Cefpodoxime	15	137	16
other	vaginal side effects	Reproductive system and breast disorders	Ciprofloxacin	8	137	8
other	vaginal side effects	Reproductive system and breast disorders	Cefpodoxime	7	137	7
other	nausea	Gastrointestinal disorders	Ciprofloxacin	13	137	13
other	nausea	Gastrointestinal disorders	Cefpodoxime	8	137	8
other	loose stools	Gastrointestinal disorders	Ciprofloxacin	7	137	7
other	loose stools	Gastrointestinal disorders	Cefpodoxime	9	137	9

1 to 10 of 14Source ClinicalTrials.gov

See all 14 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Ciprofloxacin
Total, all-cause mortality	Cefpodoxime
Total, other adverse events	Ciprofloxacin	41	137
Total, other adverse events	Cefpodoxime	37	137
Total, serious adverse events	Ciprofloxacin	0	150
Total, serious adverse events	Cefpodoxime	0	150

Source ClinicalTrials.gov

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as
22318279	RESULT

Source PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons1

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison
Ciprofloxacin vs Cefpodoxime: serious adverse events

Source Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00194532

GET https://conductscience.org/api/trials/v1/NCT00194532/registered

API reference For AI assistants