Trial · NCT00208091
Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
NCT00208091, Phase 4, Completed, Columbia University; results first posted 2014-05-09
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia. Trials, record NCT00208091. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00208091
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Quantifying Musical Performance After Treatment With Myobloc in Musician's Dystonia
- NCT number
- NCT00208091
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 16 participants, actual
- Lead sponsor
- Columbia University
- Conditions
- Focal Dystonia
- Interventions
- Botulinum toxin, type B
- First posted
- 2005-09-21
- Last updated
- 2014-05-09
- Results first posted
- 2014-05-09
Source ClinicalTrials.gov
Registered outcomes3
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Note Errors (Related to Errors in Duration) | Baseline and 6 weeks post-injection | Note errors (related to errors in duration in msec) were obtained as measures of difference between the affected and unaffected hands--taking the musical instrument digital interface (MIDI) note output from four musical sequences of 8 to 16 notes played. It was calculated by averaging the sequences for each hand, and deriving the square root of the mean of the square of the differences (root mean square error, in msec) in MIDI. |
| Primary | Note Errors (Related to Errors in Loudness) | Baseline and 6 weeks post-injection | Note errors (related to errors in loudness) were obtained as a measure of difference between the affected and unaffected hands--taking the musical instrument digital interface (MIDI) note loudness data (decibels) from four musical sequences of 8 to 16 notes. It was calculated by averaging sequences for each hand and taking the square root of the mean of the square of the differences (root mean square error, in decibels) in MIDI notes. |
| Secondary | Subjective Assessment Ratings of Change | Baseline to 6 weeks after injection | Each subject assessed his or her music playing performance change subjectively from -100 percent (fully worse) to 100 percent (fully better). |
Source ClinicalTrials.gov
Outcomes3
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Note Errors (Related to Errors in Duration) | Baseline and 6 weeks post-injection | msec | MEDIAN | |
| PRIMARY | Note Errors (Related to Errors in Loudness) | Baseline and 6 weeks post-injection | decibels | MEDIAN | |
| SECONDARY | Subjective Assessment Ratings of Change | Baseline to 6 weeks after injection | percentage change | MEAN |
Source ClinicalTrials.gov
Results by group5
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Note Errors (Related to Errors in Duration) | Note Errors (Related to Errors in Duration), Baseline | 8.20 | Standard Error 8.49 | msec | |
| Note Errors (Related to Errors in Duration) | Note Errors (Related to Errors in Duration), Post-injection | 5.79 | Standard Error 4.00 | msec | |
| Note Errors (Related to Errors in Loudness) | Note Errors, Baseline | 10.06 | Standard Error 1.28 | decibels | |
| Note Errors (Related to Errors in Loudness) | Note Errors, Post-injection | 8.43 | Standard Error 1.63 | decibels | |
| Subjective Assessment Ratings of Change | Post-injection Subjective Change | 30 | Standard Deviation 29.3 | percentage change |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Botulinum Toxin, Type B | 16 | |
| Overall Study | COMPLETED | Botulinum Toxin, Type B | 16 | |
| Overall Study | NOT COMPLETED | Botulinum Toxin, Type B | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Botulinum Toxin, Type B | ||
| Total, other adverse events | Botulinum Toxin, Type B | 0 | 16 |
| Total, serious adverse events | Botulinum Toxin, Type B | 0 | 16 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00208091
GET https://conductscience.org/api/trials/v1/NCT00208091/registered