Trial · NCT00222235
Adjunctive Treatment for Decreasing Symptoms of Schizophrenia
NCT00222235, Phase 2, Phase 3, Completed, University of Maryland, Baltimore
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Adjunctive Treatment for Decreasing Symptoms of Schizophrenia. Trials, record NCT00222235. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00222235
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Adjunctive Treatment for Decreasing Symptoms of Schizophrenia
- NCT number
- NCT00222235
- Status
- Completed
- Phases
- Phase 2, Phase 3
- Enrollment
- 240 participants
- Lead sponsor
- University of Maryland, Baltimore
- Conditions
- Schizophrenia, Schizoaffective Disorder
- Interventions
- d-cycloserine, glycine, placebo
- First posted
- 2005-09-22
- Last updated
- 2019-08-20
Source ClinicalTrials.gov
Registered outcomes4
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | changes from baseline in negative symptoms measured on SANS at 4,8,12 and 16 weeks. | ||
| Primary | change from baseline on neurocognitive battery measured at 16 weeks. | ||
| Secondary | change in psychotic and depressive symptoms measured at 4,8,12, and 16 weeks. | ||
| Secondary | changes in extrapyramidal side effects at 4,8,12 and 16 weeks. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 17898352 | DERIVED |
Source PubMed
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01MH059807 | TREATMENT OF NEGATIVE SYMPTOMS &COGNITIVE IMPAIRMENTS | CARPENTER, WILLIAM T. | UNIVERSITY OF MARYLAND BALTIMORE | NATIONAL INSTITUTE OF MENTAL HEALTH | 2000 to 2003 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00222235
GET https://conductscience.org/api/trials/v1/NCT00222235/registered