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Trial · NCT00223691

Treatment of Orthostatic Hypotension in Autonomic Failure

NCT00223691, Phase 1, Completed, Vanderbilt University

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Treatment of Orthostatic Hypotension in Autonomic Failure. Trials, record NCT00223691. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00223691

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Treatment of Orthostatic Hypotension in Autonomic Failure
NCT number
NCT00223691
Status
Completed
Phases
Phase 1
Enrollment
389 participants, actual
Lead sponsor
Vanderbilt University
Conditions
Autonomic Failure, Orthostatic Hypotension
Interventions
Atomoxetine, Acarbose, Pyridostigmine Bromide, Yohimbine, Midodrine HCl, placebo, Modafinil, Octreotide, water intake, Diphenhydramine Hydrochloride, Ranitidine HCL, Tranylcypromine, Ergotamine/ Caffeine, Celecoxib, Pseudoephedrine, Methylphenidate, Indomethacin, Ibuprofen, Oxymetazoline 0.05% nasal solution, Bovril, Acetazolamide, Rivastigmine tartrate, Carbidopa/levodopa, Inflatable abdominal binder, inflatable abdominal binder (sham)
First posted
2005-09-22
Last updated
2017-01-18

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryIncrease in seated systolic blood pressure 1-hr post drug compared to baseline.1.5-4 hours
SecondaryIncrease in standing time 1-hr post drug compared to baseline1.5-4 hours

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers18

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
9727818RESULTPubMed
10662747RESULTPubMed
11904109RESULTPubMed
11927799RESULTPubMed
12119802RESULTPubMed
12832331RESULTPubMed
15066944RESULTPubMed
15710782RESULTPubMed
15738343RESULTPubMed
17515447RESULTPubMed

1 to 10 of 18

See all 18 papers

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00223691

GET https://conductscience.org/api/trials/v1/NCT00223691/registered