Trial · NCT00248807
A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
NCT00248807, Not applicable, Completed, VA Office of Research and Development; results first posted 2014-06-23
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury. Trials, record NCT00248807. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00248807
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A Study of Blood Pressure and Blood Supply to the Brain in Persons With a Spinal Cord Injury.
- NCT number
- NCT00248807
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 30 participants, actual
- Lead sponsor
- VA Office of Research and Development
- Conditions
- Orthostatic Hypotension, Spinal Cord Injuries
- Interventions
- 1.25 mg enalaprilat IV, Head up tilt (HUT)
- First posted
- 2005-11-04
- Last updated
- 2025-02-25
- Results first posted
- 2014-06-23
- Limitations and caveats
- Did not assess carbon dioxide levels or the severity of spinal cord injury, which may have contributed to the results.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Systolic Blood Pressure | acute testing | Systolic blood pressure during head-up tilt in subjects with spinal cord injury without drug intervention |
| Secondary | Cerebral Blood Flow | acute testing | Measurement of middle cerebral artery blood flow velocity supine and during head-up tilt |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Systolic Blood Pressure | acute testing | convenience sample | mmHg | MEAN |
| SECONDARY | Cerebral Blood Flow | acute testing | cm/sec | MEAN |
Source ClinicalTrials.gov
Results by group8
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Systolic Blood Pressure | ARM 1 | 123 | Standard Deviation 37 | mmHg | |
| Systolic Blood Pressure | ARM 2 | 125 | Standard Deviation 15 | mmHg | |
| Systolic Blood Pressure | ARM 3 | 119 | Standard Deviation 26 | mmHg | |
| Systolic Blood Pressure | ARM 4 | 122 | Standard Deviation 14 | mmHg | |
| Cerebral Blood Flow | ARM 1 | 45.95 | Standard Deviation 8.71 | cm/sec | |
| Cerebral Blood Flow | ARM 2 | 42.52 | Standard Deviation 15.69 | cm/sec | |
| Cerebral Blood Flow | ARM 3 | 46.93 | Standard Deviation 7.66 | cm/sec | |
| Cerebral Blood Flow | ARM 4 | 37.38 | Standard Deviation 4.44 | cm/sec |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Subjects With Spinal Cord Injury (SCI) | 19 | |
| Overall Study | STARTED | Subjects Without SCI (Non-SCI) | 11 | |
| Overall Study | COMPLETED | Subjects With Spinal Cord Injury (SCI) | 19 | |
| Overall Study | COMPLETED | Subjects Without SCI (Non-SCI) | 11 | |
| Overall Study | NOT COMPLETED | Subjects With Spinal Cord Injury (SCI) | 0 | |
| Overall Study | NOT COMPLETED | Subjects Without SCI (Non-SCI) | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals12
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | ARM 1 | ||
| Total, all-cause mortality | ARM 2 | ||
| Total, all-cause mortality | ARM 3 | ||
| Total, all-cause mortality | ARM 4 | ||
| Total, other adverse events | ARM 1 | 0 | 19 |
| Total, other adverse events | ARM 2 | 0 | 11 |
| Total, other adverse events | ARM 3 | 0 | 19 |
| Total, other adverse events | ARM 4 | 0 | 11 |
| Total, serious adverse events | ARM 1 | 0 | 19 |
| Total, serious adverse events | ARM 2 | 0 | 11 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse event totalsPapers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 18850311 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00248807
GET https://conductscience.org/api/trials/v1/NCT00248807/registered