Trial · NCT00286481
Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia
NCT00286481, Phase 3, Completed, Takeda
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia. Trials, record NCT00286481. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00286481
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Lapaquistat Acetate Alone or Combined With Simvastatin in Subjects With Hypercholesterolemia
- NCT number
- NCT00286481
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 1,362 participants, actual
- Lead sponsor
- Takeda
- Conditions
- Hypercholesterolemia
- Interventions
- Lapaquistat acetate and simvastatin, Lapaquistat acetate and simvastatin, Simvastatin
- First posted
- 2006-02-03
- Last updated
- 2012-05-24
Source ClinicalTrials.gov
Registered outcomes21
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change from Baseline in Low Density Lipoprotein cholesterol | Week 12 or Final Visit | |
| Secondary | Adverse Events | Weeks: 2, 4, 8, and 12 or Final Visit | |
| Secondary | Physical Examination | Week 12 or Final Visit | |
| Secondary | Safety Laboratory Tests | Weeks: 2, 4, 8, and 12 or Final Visit | |
| Secondary | 12- lead Electrocardiogram assessments | Week 12 or Final Visit | |
| Secondary | Best Corrected Visual Acuity results | Week 12 or Final Visit | |
| Secondary | Vital Signs | Weeks: 2, 4, 8, and 12 or Final Visit | |
| Secondary | Change from Baseline in Triglycerides | Week 12 or Final Visit | |
| Secondary | Change from Baseline in Total Cholesterol | Week 12 or Final Visit | |
| Secondary | Change from Baseline in High Density Lipoprotein cholesterol | Week 12 or Final Visit |
1 to 10 of 21Source ClinicalTrials.gov
See all 21 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 21518985 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00286481
GET https://conductscience.org/api/trials/v1/NCT00286481/registered?page=2