Trial · NCT00296647
Smoking Cessation Intervention: Effectiveness in Primary Care
NCT00296647, Phase 4, Completed, University of Wisconsin, Madison; results first posted 2011-11-30
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Smoking Cessation Intervention: Effectiveness in Primary Care. Trials, record NCT00296647. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00296647
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Smoking Cessation Intervention: Effectiveness in Primary Care
- NCT number
- NCT00296647
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 1,346 participants, actual
- Lead sponsor
- University of Wisconsin, Madison
- Conditions
- Tobacco Dependence
- Interventions
- nicotine patch, nicotine patch, nicotine lozenge, bupropion, patch + lozenge, bupropion + lozenge
- First posted
- 2006-02-27
- Last updated
- 2015-10-14
- Results first posted
- 2011-11-30
- Limitations and caveats
The present study is limited to some extent by the fact that self-reported abstinence was not biochemically confirmed. However, there is evidence that self-reported abstinence rates are generally accurate in low-contact effectiveness studies.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | 6 Month Self-reported Abstinence From Smoking | 6 months | Primary postquit outcomes was 7-day point prevalence abstinence (0, abstinent; 1, smoking) at 6 months (based on the week 24 interview) |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | 6 Month Self-reported Abstinence From Smoking | 6 months | intent to treat | participants | NUMBER |
Source ClinicalTrials.gov
Results by group5
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| 6 Month Self-reported Abstinence From Smoking | Patch | 50 | participants | ||
| 6 Month Self-reported Abstinence From Smoking | Lozenge | 52 | participants | ||
| 6 Month Self-reported Abstinence From Smoking | Bupropion | 45 | participants | ||
| 6 Month Self-reported Abstinence From Smoking | Patch + Lozenge | 75 | participants | ||
| 6 Month Self-reported Abstinence From Smoking | Buproion + Lozenge | 80 | participants |
Source ClinicalTrials.gov
Participant flow15
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Patch | 282 | |
| Overall Study | STARTED | Nicotine Lozenge | 261 | |
| Overall Study | STARTED | Bupropion | 256 | |
| Overall Study | STARTED | Patch + Lozenge | 279 | |
| Overall Study | STARTED | Buproion + Lozenge | 268 | |
| Overall Study | COMPLETED | Patch | 250 | |
| Overall Study | COMPLETED | Nicotine Lozenge | 233 | |
| Overall Study | COMPLETED | Bupropion | 222 | |
| Overall Study | COMPLETED | Patch + Lozenge | 262 | |
| Overall Study | COMPLETED | Buproion + Lozenge | 248 |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 participant flowAdverse events15
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | skin irritation | Skin and subcutaneous tissue disorders | Patch | 15 | 282 | 15 |
| other | skin irritation | Skin and subcutaneous tissue disorders | Nicotine Lozenge | 3 | 261 | 3 |
| other | skin irritation | Skin and subcutaneous tissue disorders | Bupropion | 6 | 256 | 6 |
| other | skin irritation | Skin and subcutaneous tissue disorders | Patch + Lozenge | 5 | 279 | 5 |
| other | skin irritation | Skin and subcutaneous tissue disorders | Buproion + Lozenge | 3 | 268 | 3 |
| other | nausea | Gastrointestinal disorders | Patch | 3 | 282 | 3 |
| other | nausea | Gastrointestinal disorders | Nicotine Lozenge | 12 | 261 | 12 |
| other | nausea | Gastrointestinal disorders | Bupropion | 6 | 256 | 6 |
| other | nausea | Gastrointestinal disorders | Patch + Lozenge | 8 | 279 | 8 |
| other | nausea | Gastrointestinal disorders | Buproion + Lozenge | 3 | 268 | 3 |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 adverse eventsAdverse event totals15
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Patch | ||
| Total, all-cause mortality | Nicotine Lozenge | ||
| Total, all-cause mortality | Bupropion | ||
| Total, all-cause mortality | Patch + Lozenge | ||
| Total, all-cause mortality | Buproion + Lozenge | ||
| Total, other adverse events | Patch | 18 | 282 |
| Total, other adverse events | Nicotine Lozenge | 15 | 261 |
| Total, other adverse events | Bupropion | 12 | 256 |
| Total, other adverse events | Patch + Lozenge | 13 | 279 |
| Total, other adverse events | Buproion + Lozenge | 6 | 268 |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 adverse event totalsPapers2
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| P50DA019706 | Tobacco Dependence: Treatment and Outcomes | BAKER, TIMOTHY B | UNIVERSITY OF WISCONSIN-MADISON | NATIONAL INSTITUTE ON DRUG ABUSE | 2004 to 2008 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00296647
GET https://conductscience.org/api/trials/v1/NCT00296647/registered