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Trial · NCT00312377

Results by group18

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-Free Survival (PFS) in the Overall PopulationVandetanib 100 mg Plus Docetaxel17.395% Confidence Interval 15 to 18Weeks
Progression-Free Survival (PFS) in the Overall PopulationPlacebo Plus Docetaxel1495% Confidence Interval 12.7 to 16.9Weeks
Progression-Free Survival (PFS) in the Female PopulationVandetanib 100 mg Plus Docetaxel20.195% Confidence Interval 17.9 to 23.9Weeks
Progression-Free Survival (PFS) in the Female PopulationPlacebo Plus Docetaxel18.395% Confidence Interval 15 to 22.1Weeks
Overall Survival (OS) in the Overall PopulationVandetanib 100 mg Plus Docetaxel10.695% Confidence Interval 9.6 to 11.5Months
Overall Survival (OS) in the Overall PopulationPlacebo Plus Docetaxel1095% Confidence Interval 9.2 to 10.8Months
Overall Survival (OS) in the Female PopulationVandetanib 100 mg Plus Docetaxel12.795% Confidence Interval 10.5 to 17.1Months
Overall Survival (OS) in the Female PopulationPlacebo Plus Docetaxel14.295% Confidence Interval 10.8 to 16.2Months
Objective Response Rate (ORR)Vandetanib 100 mg Plus Docetaxel120Participants
Objective Response Rate (ORR)Placebo Plus Docetaxel71Participants
Disease Control Rate (DCR)Vandetanib 100 mg Plus Docetaxel413Participants
Disease Control Rate (DCR)Placebo Plus Docetaxel380Participants
Duration of Response (DoR)Vandetanib 100 mg Plus Docetaxel29.9Full Range 7.14 to 72.29Weeks
Duration of Response (DoR)Placebo Plus Docetaxel19.7Full Range 9.71 to 41.86Weeks
Time to Deterioration of Disease-related Symptoms (TDS) by Functional Assessment of Cancer Therapy - Lung (FACT-L) Lung Cancer Subscale (LCS).Vandetanib 100 mg Plus Docetaxel15Inter-Quartile Range 6.1 to 82.3Weeks
Time to Deterioration of Disease-related Symptoms (TDS) by Functional Assessment of Cancer Therapy - Lung (FACT-L) Lung Cancer Subscale (LCS).Placebo Plus Docetaxel11.9Inter-Quartile Range 6.0 to 28.1Weeks
Time to Deterioration of Disease-related Symptoms (TDS) by FACT-L Pulmonary Symptom Index (PSI)Vandetanib 100 mg Plus Docetaxel12.3Inter-Quartile Range 5.9 to 36.7Weeks
Time to Deterioration of Disease-related Symptoms (TDS) by FACT-L Pulmonary Symptom Index (PSI)Placebo Plus Docetaxel11.9Inter-Quartile Range 6 to 28.4Weeks

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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