Trial · NCT00318474
Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy
NCT00318474, Phase 3, Terminated, St. Joseph's Hospital and Medical Center, Phoenix; results first posted 2014-10-01
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy. Trials, record NCT00318474. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00318474
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Mycophenolate Mofetil (MMF) in Patients With IgA Nephropathy
- NCT number
- NCT00318474
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 184 participants, actual
- Lead sponsor
- St. Joseph's Hospital and Medical Center, Phoenix
- Conditions
- IgA Nephropathy
- Interventions
- Mycophenolate Mofetil (MMF), MMF Placebo, ACEi, FOS
- First posted
- 2006-04-26
- Last updated
- 2016-03-07
- Results first posted
- 2014-10-01
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Proteinuria - Uprotein/Creatinine Ratio | Plan was to measure uprotein/creatinine ratio for 12 months on MMF or placebo, and then 12 months post-treatment. Data given after 6 months MMF/placebo. | Urine protein/creatinine ratio after 6 months treatment with MMF or placebo. |
| Secondary | Change in Estimated Glomerular Filtration Rate (GFR) to Less Than 60% of the Baseline Level | 12 months |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Proteinuria - Uprotein/Creatinine Ratio | Plan was to measure uprotein/creatinine ratio for 12 months on MMF or placebo, and then 12 months post-treatment. Data given after 6 months MMF/placebo. | ratio | MEAN | |
| SECONDARY | Change in Estimated Glomerular Filtration Rate (GFR) to Less Than 60% of the Baseline Level | 12 months |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Proteinuria - Uprotein/Creatinine Ratio | Mycophenolate Mofetil (MMF) | 1.40 | Standard Deviation 0.72 | ratio | |
| Change in Proteinuria - Uprotein/Creatinine Ratio | Placebo | 1.58 | Standard Deviation 1.07 | ratio |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Mycophenolate Mofetil (MMF) | 25 | |
| Overall Study | STARTED | Placebo | 27 | |
| Overall Study | COMPLETED | Mycophenolate Mofetil (MMF) | 7 | |
| Overall Study | COMPLETED | Placebo | 10 | |
| Overall Study | NOT COMPLETED | Mycophenolate Mofetil (MMF) | 18 | |
| Overall Study | NOT COMPLETED | Placebo | 17 |
Source ClinicalTrials.gov
Adverse events22
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | backache | Musculoskeletal and connective tissue disorders | Mycophenolate Mofetil (MMF) | 6 | 25 | |
| other | backache | Musculoskeletal and connective tissue disorders | Placebo | 6 | 27 | |
| other | common cold | Respiratory, thoracic and mediastinal disorders | Mycophenolate Mofetil (MMF) | 5 | 25 | |
| other | common cold | Respiratory, thoracic and mediastinal disorders | Placebo | 7 | 27 | |
| other | coughing | Respiratory, thoracic and mediastinal disorders | Mycophenolate Mofetil (MMF) | 9 | 25 | |
| other | coughing | Respiratory, thoracic and mediastinal disorders | Placebo | 9 | 27 | |
| other | diarrhea | Gastrointestinal disorders | Mycophenolate Mofetil (MMF) | 4 | 25 | |
| other | diarrhea | Gastrointestinal disorders | Placebo | 6 | 27 | |
| other | edema | General disorders | Mycophenolate Mofetil (MMF) | 5 | 25 | |
| other | edema | General disorders | Placebo | 3 | 27 |
1 to 10 of 22Source ClinicalTrials.gov
See all 22 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Mycophenolate Mofetil (MMF) | ||
| Total, all-cause mortality | Placebo | ||
| Total, other adverse events | Mycophenolate Mofetil (MMF) | 25 | 25 |
| Total, other adverse events | Placebo | 27 | 27 |
| Total, serious adverse events | Mycophenolate Mofetil (MMF) | 1 | 25 |
| Total, serious adverse events | Placebo | 1 | 27 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Mycophenolate Mofetil (MMF) vs Placebo: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00318474
GET https://conductscience.org/api/trials/v1/NCT00318474/events?page=2