Trial · NCT00342381
Fatigue in Multiple Sclerosis: Evaluated With 3 MRI and Transcranial Magnetic Stimulation
NCT00342381, Phase 2, Completed, University of Aarhus
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Fatigue in Multiple Sclerosis: Evaluated With 3 MRI and Transcranial Magnetic Stimulation. Trials, record NCT00342381. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00342381
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Fatigue in Multiple Sclerosis: Evaluated With 3 MRI and Transcranial Magnetic Stimulation
- NCT number
- NCT00342381
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 120 participants, estimated
- Lead sponsor
- University of Aarhus
- Conditions
- Multiple Sclerosis, Fatigue
- Interventions
- 3,4-diaminopyridine, Placebo
- First posted
- 2006-06-21
- Last updated
- 2007-12-17
Source ClinicalTrials.gov
Registered outcomes16
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Subjective fatigue (FSS) | Weeks | |
| Primary | Maximal voluntary isometric contraction, central activation before and after exercise | at the time of investigation | |
| Primary | Digit Symbol-Coding scores | Weeks | |
| Primary | Changes in normal appearing white matter and normal appearing gray matter (MRS-, MTI- and DTI- parameters) | at the time of MRI | |
| Primary | Cortical atrophy | at the time of MRI | |
| Primary | Intracortical inhibition/facilitation determined by transcranial magnetic stimulation (+/- 3,4-diaminopyridine) | at the time of investigation | |
| Secondary | Subjective fatigue (MFI-20, Danish version) | Weeks | |
| Secondary | Rapid voluntary twitches | at the time of investigation | |
| Secondary | 6 minute walk test | at the time of investigation | |
| Secondary | 9-hole peg test | at the time of investigation |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| Symbol Coding | Primary outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00342381
GET https://conductscience.org/api/trials/v1/NCT00342381/registered