Trial · NCT00364689
RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial
NCT00364689, Phase 3, Terminated, University of Miami; results first posted 2019-09-17
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial. Trials, record NCT00364689. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00364689
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- RICE Trial: Rifaximin In Chronic Hepatic Encephalopathy - A Randomized, Controlled Trial
- NCT number
- NCT00364689
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 13 participants, actual
- Lead sponsor
- University of Miami
- Conditions
- Hepatic Encephalopathy
- Interventions
- Rifaximin, Lactulose, Placebo
- First posted
- 2006-08-16
- Last updated
- 2019-09-17
- Results first posted
- 2019-09-17
- Limitations and caveats
Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed.
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Hospitalizations for Hepatic Encephalopathy (HE) | Month 7 | |
| Primary | Changes in Psychometric Testing During Study Period | Month 7 | |
| Secondary | Number of Hospitalization Days for All Causes | Month 7 | |
| Secondary | Death or Survival to Liver Transplantation | Month 7 | |
| Secondary | Rate of Adverse Events With Rifaximin Treatment | Month 7 |
Source ClinicalTrials.gov
Outcomes5
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Hospitalizations for Hepatic Encephalopathy (HE) | Month 7 | Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed. | ||
| PRIMARY | Changes in Psychometric Testing During Study Period | Month 7 | Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed. | ||
| SECONDARY | Number of Hospitalization Days for All Causes | Month 7 | Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed. | ||
| SECONDARY | Death or Survival to Liver Transplantation | Month 7 | Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed. | ||
| SECONDARY | Rate of Adverse Events With Rifaximin Treatment | Month 7 | Outcome measure data is not reported as the study was terminated due to difficulty with enrolling participants. Collection of data ceased and data analysis was not performed. Data collected is no longer available as the retention period has passed. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | All Participants | 13 | |
| Overall Study | COMPLETED | All Participants | 12 | |
| Overall Study | NOT COMPLETED | All Participants | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | All Study Participants | 0 | 0 |
| Total, other adverse events | All Study Participants | 0 | 0 |
| Total, serious adverse events | All Study Participants | 0 | 0 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00364689
GET https://conductscience.org/api/trials/v1/NCT00364689/registered