Trial · NCT00369746
STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse
NCT00369746, Completed, New York State Psychiatric Institute; results first posted 2014-05-09
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse. Trials, record NCT00369746. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00369746
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- STAR*D Alcohol: Treatment of Depression Concurrent With Alcohol Abuse
- NCT number
- NCT00369746
- Status
- Completed
- Enrollment
- 674 participants, actual
- Lead sponsor
- New York State Psychiatric Institute
- Conditions
- Major Depressive Disorder, Alcohol Use Disorder
- Interventions
- citalopram
- First posted
- 2006-08-29
- Last updated
- 2014-05-09
- Results first posted
- 2014-05-09
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Quick Inventory of Depression- Self Report 16 | study exit visit, at Week 12 | Quick Inventory of Depression- Self Report assesses 16 depressive symptoms experienced in the past week, based on self-rating, measured at study exit visit Scale range: Each of the four possible answers to each quiz is given an ascending numerical value from 0 to 3, and the total test score is the sum of the following: The highest number from questions 1-4 The number from question 5 The highest number from questions 6-9 The total of each question from 10-14 The highest number from questions 15-16 Total scoring ranges (0-48): 0-5, No Depression Likely 6-10, Possibly Mildly Depressed 11-15, Moderate Depression 16-20, Severe Depression 21 or Over, Very Severe Depression |
| Secondary | Timeline Follow Back (TLFB) Average Drinks Per Drinking Day | 30 days | This variable reports average drinks/drinking day in a pre-defined time frame. |
| Secondary | Quantitative Substance Use Inventory ((SUI) | 30 days | Quantitative Substance Use Inventory ((SUI) Measure substance use Administered at either week 12 or 14: Any Illicit Drug Using in last 30 days |
| Secondary | Timeline Follow Back (TLFB) Drinking Days Per 30 Days | 30 days | This variable reports drinking days in a pre-defined time frame. |
| Secondary | Timeline Follow Back (TLFB) Maximum Drinks Per Drinking Day | 30 days | This variable reports maximum drinks per drinking day in a pre-defined time frame. |
Source ClinicalTrials.gov
Outcomes5
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Quick Inventory of Depression- Self Report 16 | study exit visit, at Week 12 | All participants who met entry criteria for alcohol abuse or dependence per protocol. | units on a scale | MEAN |
| SECONDARY | Timeline Follow Back (TLFB) Average Drinks Per Drinking Day | 30 days | Subjects who met entering criteria for alcohol abuse or alcohol dependence per protocol | drinks per drinking day | MEAN |
| SECONDARY | Quantitative Substance Use Inventory ((SUI) | 30 days | All participants who met entry criteria for alcohol abuse or dependence per protocol. | Days | MEAN |
| SECONDARY | Timeline Follow Back (TLFB) Drinking Days Per 30 Days | 30 days | Subjects who met entering criteria for alcohol abuse or alcohol dependence per protocol | days | MEAN |
| SECONDARY | Timeline Follow Back (TLFB) Maximum Drinks Per Drinking Day | 30 days | Subjects who met entering criteria for alcohol abuse or alcohol dependence per protocol | drinks | MEAN |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Quick Inventory of Depression- Self Report 16 | Alcoholic | 9.3 | Standard Deviation 6.1 | units on a scale | |
| Quick Inventory of Depression- Self Report 16 | Major Depression Only | 8.9 | Standard Deviation 5.7 | units on a scale | |
| Timeline Follow Back (TLFB) Average Drinks Per Drinking Day | Alcoholic | 2.9 | Standard Deviation 2.6 | drinks per drinking day | |
| Quantitative Substance Use Inventory ((SUI) | Alcoholic | 2.4 | Standard Deviation 7.12 | Days | |
| Timeline Follow Back (TLFB) Drinking Days Per 30 Days | Alcoholic | 8.1 | Standard Deviation 7.8 | days | |
| Timeline Follow Back (TLFB) Maximum Drinks Per Drinking Day | Alcoholic | 4.9 | Standard Deviation 3.9 | drinks |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Alcohol Abuse or Dependence | 138 | |
| Overall Study | STARTED | Major Depression Only | 536 | |
| Overall Study | COMPLETED | Alcohol Abuse or Dependence | 138 | |
| Overall Study | COMPLETED | Major Depression Only | 536 | |
| Overall Study | NOT COMPLETED | Alcohol Abuse or Dependence | 0 | |
| Overall Study | NOT COMPLETED | Major Depression Only | 0 |
Source ClinicalTrials.gov
Adverse events12
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Hospitalilization GMC | General disorders | Alcohol Abuse or Dependence | 5 | 138 | 5 |
| serious | Hospitalilization GMC | General disorders | Major Depression Only | 16 | 536 | 16 |
| serious | Medical illness without hospitalizaiton | General disorders | Alcohol Abuse or Dependence | 1 | 138 | 1 |
| serious | Medical illness without hospitalizaiton | General disorders | Major Depression Only | 1 | 536 | 1 |
| serious | Psychiatric hospitalization, substance abuse | Psychiatric disorders | Alcohol Abuse or Dependence | 2 | 138 | 2 |
| serious | Psychiatric hospitalization, substance abuse | Psychiatric disorders | Major Depression Only | 1 | 536 | 1 |
| serious | Death, non-suicide | General disorders | Alcohol Abuse or Dependence | 0 | 138 | 0 |
| serious | Death, non-suicide | General disorders | Major Depression Only | 1 | 536 | 1 |
| serious | Psychiatric hospitalization (worsening depression) | Psychiatric disorders | Alcohol Abuse or Dependence | 0 | 138 | 0 |
| serious | Psychiatric hospitalization (worsening depression) | Psychiatric disorders | Major Depression Only | 2 | 536 | 2 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Alcohol Abuse or Dependence | ||
| Total, all-cause mortality | Major Depression Only | ||
| Total, other adverse events | Alcohol Abuse or Dependence | 0 | 138 |
| Total, other adverse events | Major Depression Only | 0 | 536 |
| Total, serious adverse events | Alcohol Abuse or Dependence | 8 | 138 |
| Total, serious adverse events | Major Depression Only | 23 | 536 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01AA013303 | ALCOHOL USE DISORDER IN PATIENTS TREATED FOR DEPRESSION | MC GRATH, PATRICK J | NEW YORK STATE PSYCHIATRIC INSTITUTE | NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM | 2001 to 2004 |
Source NIH RePORTER
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Alcohol Abuse or Dependence vs Major Depression Only: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00369746
GET https://conductscience.org/api/trials/v1/NCT00369746/registered