Trial · NCT00378079
Methadone Maintenance for Prisoners
NCT00378079, Phase 3, Completed, Friends Research Institute, Inc.; results first posted 2014-04-03
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Methadone Maintenance for Prisoners. Trials, record NCT00378079. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00378079
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Methadone Maintenance for Prisoners
- NCT number
- NCT00378079
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 211 participants, actual
- Lead sponsor
- Friends Research Institute, Inc.
- Conditions
- Heroin Addiction
- Interventions
- Counseling Only, Counseling + Transfer, Counseling + Methadone
- First posted
- 2006-09-19
- Last updated
- 2014-04-03
- Results first posted
- 2014-04-03
- Limitations and caveats
See 2009 manuscript published in the Journal of Substance Abuse Treatment for the a discussion of study limitations. The study was conducted only on males from Baltimore. For results regarding HIV risk behaviors see manuscript by Wilson et. al.
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Treatment Retention in the Community | one year post prison release | days in community treatment |
| Primary | Heroin Use | results at one year post prison release | opioid urine test results-percent of participants who were opioid-positive |
| Primary | Cocaine Use | one year post prison release | cocaine urine test results-percent of participants testing positive for cocaine |
| Primary | HIV-risk Behaviors | one year | |
| Primary | Criminal Activity | one year post prison release | self reported days of criminal activity |
| Secondary | Employment | one year | number of days employed, past 30 days-self report, assessed one year post-prison release |
Source ClinicalTrials.gov
Outcomes6
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Treatment Retention in the Community | one year post prison release | Days in community treatment | MEAN | |
| PRIMARY | Heroin Use | results at one year post prison release | Includes participants who provided urine samples at the time their 1-year post-prison release assessment was due-excludes those assessed later or reincarcerated | % participants opioid positive | NUMBER |
| PRIMARY | Cocaine Use | one year post prison release | Includes participants who provided urine samples at the time their 1-year post-prison release assessment was due, excludes those assessed later or reincarcerated | percent cocaine positive participants | NUMBER |
| PRIMARY | HIV-risk Behaviors | one year | |||
| PRIMARY | Criminal Activity | one year post prison release | number of days | MEAN | |
| SECONDARY | Employment | one year | number of days employed, past 30 | MEAN |
Source ClinicalTrials.gov
Results by group15
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Treatment Retention in the Community | 1 Counseling Only in Prison | 23.1 | Standard Deviation 72.5 | Days in community treatment | |
| Treatment Retention in the Community | 2 Counseling Only in Prison, With Initiation of Methadone Main | 91.3 | Standard Deviation 144.6 | Days in community treatment | |
| Treatment Retention in the Community | 3 Counseling and Methadone Maintenance in Prison, With Continu | 166.0 | Standard Deviation 166.4 | Days in community treatment | |
| Heroin Use | 1 Counseling Only in Prison | 65.6 | % participants opioid positive | ||
| Heroin Use | 2 Counseling Only in Prison, With Initiation of Methadone Main | 48.7 | % participants opioid positive | ||
| Heroin Use | 3 Counseling and Methadone Maintenance in Prison, With Continu | 25.0 | % participants opioid positive | ||
| Cocaine Use | 1 Counseling Only in Prison | 71.9 | percent cocaine positive participants | ||
| Cocaine Use | 2 Counseling Only in Prison, With Initiation of Methadone Main | 66.6 | percent cocaine positive participants | ||
| Cocaine Use | 3 Counseling and Methadone Maintenance in Prison, With Continu | 43.2 | percent cocaine positive participants | ||
| Criminal Activity | 1 Counseling Only in Prison | 106.7 | Standard Deviation 128.7 | number of days |
1 to 10 of 15Source ClinicalTrials.gov
See all 15 results by groupParticipant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | 1 Counseling Only in Prison | 70 | |
| Overall Study | STARTED | 2 Counseling Only in Prison, With Initiation of Methadone Main | 70 | |
| Overall Study | STARTED | 3 Counseling and Methadone Maintenance in Prison, With Continu | 71 | |
| Overall Study | COMPLETED | 1 Counseling Only in Prison | 64 | |
| Overall Study | COMPLETED | 2 Counseling Only in Prison, With Initiation of Methadone Main | 69 | |
| Overall Study | COMPLETED | 3 Counseling and Methadone Maintenance in Prison, With Continu | 71 | |
| Overall Study | NOT COMPLETED | 1 Counseling Only in Prison | 6 | |
| Overall Study | NOT COMPLETED | 2 Counseling Only in Prison, With Initiation of Methadone Main | 1 | |
| Overall Study | NOT COMPLETED | 3 Counseling and Methadone Maintenance in Prison, With Continu | 0 |
Source ClinicalTrials.gov
Adverse events6
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Death | Injury, poisoning and procedural complications | 1 Counseling Only in Prison | 6 | 70 | 6 |
| serious | Death | Injury, poisoning and procedural complications | 2 Counseling Only in Prison, With Initiation of Methadone Main | 1 | 70 | 1 |
| serious | Death | Injury, poisoning and procedural complications | 3 Counseling and Methadone Maintenance in Prison, With Continu | 1 | 71 | 1 |
| serious | hospitalizations | General disorders | 1 Counseling Only in Prison | 9 | 70 | 9 |
| serious | hospitalizations | General disorders | 2 Counseling Only in Prison, With Initiation of Methadone Main | 5 | 70 | 14 |
| serious | hospitalizations | General disorders | 3 Counseling and Methadone Maintenance in Prison, With Continu | 15 | 71 | 20 |
Source ClinicalTrials.gov
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | 1 Counseling Only in Prison | ||
| Total, all-cause mortality | 2 Counseling Only in Prison, With Initiation of Methadone Main | ||
| Total, all-cause mortality | 3 Counseling and Methadone Maintenance in Prison, With Continu | ||
| Total, other adverse events | 1 Counseling Only in Prison | 0 | 0 |
| Total, other adverse events | 2 Counseling Only in Prison, With Initiation of Methadone Main | 0 | 0 |
| Total, other adverse events | 3 Counseling and Methadone Maintenance in Prison, With Continu | 0 | 0 |
| Total, serious adverse events | 1 Counseling Only in Prison | 15 | 70 |
| Total, serious adverse events | 2 Counseling Only in Prison, With Initiation of Methadone Main | 6 | 70 |
| Total, serious adverse events | 3 Counseling and Methadone Maintenance in Prison, With Continu | 16 | 71 |
Source ClinicalTrials.gov
Papers6
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01DA016237 | Methadone Maintenance for Prisoners | KINLOCK, TIMOTHY W | FRIENDS RESEARCH INSTITUTE, INC. | NATIONAL INSTITUTE ON DRUG ABUSE | 2003 to 2007 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00378079
GET https://conductscience.org/api/trials/v1/NCT00378079/registered