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Trial · NCT00418886

Results by group20

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Progression-Free Survival (PFS) in the Overall PopulationVandetanib Plus Pemetrexed17.695% Confidence Interval 13.4 to 18.9weeks
Progression-Free Survival (PFS) in the Overall PopulationPlacebo Plus Pemetrexed11.995% Confidence Interval 11.4 to 15.9weeks
Progression-Free Survival in the Female PopulationVandetanib Plus Pemetrexed17.995% Confidence Interval 14.7 to 22.7weeks
Progression-Free Survival in the Female PopulationPlacebo Plus Pemetrexed13.095% Confidence Interval 11.1 to 17.7weeks
Overall Survival (OS)Vandetanib Plus Pemetrexed10.595% Confidence Interval 8.9 to 12.3months
Overall Survival (OS)Placebo Plus Pemetrexed9.295% Confidence Interval 7.1 to 12.0months
Objective Response Rate (ORR)Vandetanib Plus Pemetrexed19.1percentage of participants
Objective Response Rate (ORR)Placebo Plus Pemetrexed7.9percentage of participants
Disease Control Rate (DCR)Vandetanib Plus Pemetrexed56.6percentage of participants
Disease Control Rate (DCR)Placebo Plus Pemetrexed45.7percentage of participants
Duration of Response (DoR)Vandetanib Plus Pemetrexed24.195% Confidence Interval 17.4 to 30.0weeks
Duration of Response (DoR)Placebo Plus Pemetrexed24.495% Confidence Interval 18.0 to 32.0weeks
Time to Deterioration of Disease-Related Symptoms (TDS) by Lung Cancer Symptom Scale (LCSS) Total ScoreVandetanib Plus Pemetrexed18.195% Confidence Interval 15.1 to 23.6weeks
Time to Deterioration of Disease-Related Symptoms (TDS) by Lung Cancer Symptom Scale (LCSS) Total ScorePlacebo Plus Pemetrexed12.195% Confidence Interval 9.7 to 17.3weeks
Time to Deterioration of Disease-Related Symptoms by Average Symptom Burden Index (ASBI) ScoreVandetanib Plus Pemetrexed16.095% Confidence Interval 14.0 to 20.3weeks
Time to Deterioration of Disease-Related Symptoms by Average Symptom Burden Index (ASBI) ScorePlacebo Plus Pemetrexed13.495% Confidence Interval 10.3 to 17.9weeks
Longitudinal Analysis of Lung Cancer Symptom Scale Total ScoreVandetanib Plus Pemetrexed25.7Standard Error 2.85mms on a visual analogue scale
Longitudinal Analysis of Lung Cancer Symptom Scale Total ScorePlacebo Plus Pemetrexed28.3Standard Error 2.77mms on a visual analogue scale
Longitudinal Analysis of Average Symptom Burden Index ScoreVandetanib Plus Pemetrexed21.7Standard Error 2.75mms on a visual analogue scale
Longitudinal Analysis of Average Symptom Burden Index ScorePlacebo Plus Pemetrexed24.3Standard Error 2.67mms on a visual analogue scale

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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