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Trial · NCT00428948

Results by group14

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Percentage Change Per Year in Total Kidney Volume From Baseline to Month 36Tolvaptan2.777Standard Deviation 5.659Percentage change per year
Percentage Change Per Year in Total Kidney Volume From Baseline to Month 36Placebo5.608Standard Deviation 5.330Percentage change per year
Number of ADPKD Clinical Progression Events Per 100 Follow-up Years From Baseline to Month 36Tolvaptan43.94Events/100 follow-up years
Number of ADPKD Clinical Progression Events Per 100 Follow-up Years From Baseline to Month 36Placebo50.04Events/100 follow-up years
Change in Renal Function Per Year From Week 3 to Month 36Tolvaptan-2.555Standard Deviation 9.767(mg/mL)^-1 per year
Change in Renal Function Per Year From Week 3 to Month 36Placebo-3.682Standard Deviation 6.361(mg/mL)^-1 per year
Change in Mean Arterial Blood Pressure Per Year in Non-hypertensive Participants From Baseline to Month 36Tolvaptan2.561Standard Deviation 9.798mmHg
Change in Mean Arterial Blood Pressure Per Year in Non-hypertensive Participants From Baseline to Month 36Placebo2.592Standard Deviation 7.095mmHg
Area Under the Concentration-time Curve of Change in Renal Pain From Baseline to Month 36Tolvaptan-0.00Standard Deviation 1.29units on a scale
Area Under the Concentration-time Curve of Change in Renal Pain From Baseline to Month 36Placebo0.08Standard Deviation 1.43units on a scale
Number of Hypertensive Events Per 100 Follow-up Years in Non-hypertensive Participants From Baseline to Month 36Tolvaptan31.80Events/100 follow-up years
Number of Hypertensive Events Per 100 Follow-up Years in Non-hypertensive Participants From Baseline to Month 36Placebo29.60Events/100 follow-up years
Percentage of Participants With a Clinically Sustained Decrease of Blood Pressure Leading to a Sustained Reduction in Antihypertensive Therapy From Baseline to Month 36Tolvaptan6.24Percentage of participants
Percentage of Participants With a Clinically Sustained Decrease of Blood Pressure Leading to a Sustained Reduction in Antihypertensive Therapy From Baseline to Month 36Placebo5.62Percentage of participants

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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