Trial · NCT00474279
Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults
NCT00474279, Phase 1, Phase 2, Completed, University of Virginia
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults. Trials, record NCT00474279. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00474279
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effects of an Oral GH Secretagogue (MK-677) on Body Composition and Functional Ability of Older Adults
- NCT number
- NCT00474279
- Status
- Completed
- Phases
- Phase 1, Phase 2
- Enrollment
- 72 participants
- Lead sponsor
- University of Virginia
- Conditions
- Aging
- Interventions
- Orally active growth hormone secretagogue (MK-677)
- First posted
- 2007-05-16
- Last updated
- 2007-05-16
Source ClinicalTrials.gov
Registered outcomes18
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | At 12 months: 24-hour mean growth hormone concentrations | ||
| Primary | Insulin-like growth factor-I concentrations | ||
| Primary | Body weight and fat mass, specifically abdominal visceral fat | ||
| Primary | Fat-free mass | ||
| Primary | Safety determined by routine laboratory tests at 1 to 3 month intervals, yearly pap smears and mammograms | ||
| Secondary | at 12 months: Growth hormone secretory dynamics | ||
| Secondary | Isokinetic muscle strength (knee and shoulder) | ||
| Secondary | Thigh muscle cross-sectional area | ||
| Secondary | Function tests (timed walks, stair climb, chair rise) | ||
| Secondary | Quality of life assessments |
1 to 10 of 18Source ClinicalTrials.gov
See all 18 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 8954023 | BACKGROUND |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00474279
GET https://conductscience.org/api/trials/v1/NCT00474279/registered