Trial · NCT00515294

Acute and Residual Effects of Caffeinated Beer

NCT00515294, Phase 1, Phase 2, Completed, Boston University; results first posted 2017-06-28

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Acute and Residual Effects of Caffeinated Beer. Trials, record NCT00515294. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00515294

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Acute and Residual Effects of Caffeinated Beer
NCT number: NCT00515294
Status: Completed
Phases: Phase 1, Phase 2
Enrollment: 154 participants, actual
Lead sponsor: Boston University
Conditions: Neurobehavioral Manifestations, Drug Related Sleep Disturbance, Alcohol Intoxication
Interventions: Caffeinated Alcoholic Beer, Non-Caffeinated Alcoholic Beer, Caffeinated Non-Alcoholic Beer, Non-Caffeinated, Non-Alcoholic Beer
First posted: 2007-08-13
Last updated: 2017-06-28
Results first posted: 2017-06-28
Limitations and caveats: Difficulties with the driver simulator resulted in invalid data for 6 participants so their results were not included in the lane position deviation results. Inaccurate caffeine doses resulted in exclusion of 12 participants from the trial.

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Lane Position Deviation	30 minutes post dosing	The reported lane position deviation indicates the position of the car relative to the center line in feet in the driver simulator. A deviation of 0 indicates no deviation from the center line (the car is positioned farthest from the road edge). Negative numbers indicate deviations to the right of the center line with the car positioned within the lane closer to the road edge. Positive numbers indicate deviations to the left of the center line with the car positioned in the lane of oncoming traffic closer to the road edge
Secondary	Psycho-motor Vigilance Test (PVT)	30 minutes post dosing	Participants completed 10 test trials to assess their psycho-motor response using a hand held box that randomly starts a scroll of numbers in milliseconds and as soon as it starts to scroll the participant needs to press a button to stop the scrolling. The mean and standard deviations for the 10 tests were calculated as a single outcome score for each study arm. Response times were measured in milliseconds. The lower the number of milliseconds the faster the response to the random stimuli.

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Lane Position Deviation	30 minutes post dosing	Driver simulator did not work properly for 6 participants. Their data are not included.	feet	MEAN
SECONDARY	Psycho-motor Vigilance Test (PVT)	30 minutes post dosing		milliseconds	MEAN

Source ClinicalTrials.gov

Results by group8

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Spread	Units
Lane Position Deviation	1Caffeinated Alcoholic Beer	-1.25	Standard Deviation .61	feet
Lane Position Deviation	2Non-Caffeinated Alcoholic Beer	-1.36	Standard Deviation .85	feet
Lane Position Deviation	3Caffeinated Non-Alcoholic Beer	-1.22	Standard Deviation .53	feet
Lane Position Deviation	4Non-Alcoholic, Non-Caffeinated Beer	-1.21	Standard Deviation .77	feet
Psycho-motor Vigilance Test (PVT)	1Caffeinated Alcoholic Beer	278.7	Standard Deviation 46.6	milliseconds
Psycho-motor Vigilance Test (PVT)	2Non-Caffeinated Alcoholic Beer	293.3	Standard Deviation 47.0	milliseconds
Psycho-motor Vigilance Test (PVT)	3Caffeinated Non-Alcoholic Beer	233.1	Standard Deviation 22.3	milliseconds
Psycho-motor Vigilance Test (PVT)	4Non-Alcoholic, Non-Caffeinated Beer	241.8	Standard Deviation 25.6	milliseconds

Source ClinicalTrials.gov

Participant flow12

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	1Caffeinated Alcoholic Beer	38
Overall Study	STARTED	2Non-Caffeinated Alcoholic Beer	39
Overall Study	STARTED	3Caffeinated Non-Alcoholic Beer	38
Overall Study	STARTED	4Non-Alcoholic, Non-Caffeinated Beer	39
Overall Study	COMPLETED	1Caffeinated Alcoholic Beer	29
Overall Study	COMPLETED	2Non-Caffeinated Alcoholic Beer	36
Overall Study	COMPLETED	3Caffeinated Non-Alcoholic Beer	27
Overall Study	COMPLETED	4Non-Alcoholic, Non-Caffeinated Beer	35
Overall Study	NOT COMPLETED	1Caffeinated Alcoholic Beer	9
Overall Study	NOT COMPLETED	2Non-Caffeinated Alcoholic Beer	3

1 to 10 of 12Source ClinicalTrials.gov

See all 12 participant flow

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals12

The totals the trial posted for each group.

Total	Group	At risk
Total, all-cause mortality	1Caffeinated Alcohol	29
Total, all-cause mortality	2Non-Caffeinated Alcohol	36
Total, all-cause mortality	3Caffeinated Non-Alcoholic Beer	27
Total, all-cause mortality	4Non-Alcoholic, Non-Caffeinated Beer	35
Total, other adverse events	1Caffeinated Alcohol	29
Total, other adverse events	2Non-Caffeinated Alcohol	36
Total, other adverse events	3Caffeinated Non-Alcoholic Beer	27
Total, other adverse events	4Non-Alcoholic, Non-Caffeinated Beer	35
Total, serious adverse events	1Caffeinated Alcohol	29
Total, serious adverse events	2Non-Caffeinated Alcohol	36

1 to 10 of 12Source ClinicalTrials.gov

See all 12 adverse event totals

Papers1

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as
21134017	DERIVED

Source PubMed

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

Project	Title	Principal investigators	Organization	Funder	Fiscal years
R49CE000946	Research Grants to Prevent Unintentional Injuries	HOWLAND, JONATHAN	BOSTON UNIVERSITY MEDICAL CAMPUS	NATIONAL CENTER FOR INJURY PREVENTION AND CONTROL	2006 to 2008

Source NIH RePORTER

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00515294

GET https://conductscience.org/api/trials/v1/NCT00515294/registered

API reference For AI assistants