Trial · NCT00521742
Efficacy of Pioglitazone Compared to Glyburide in Treating Subjects With Type 2 Diabetes Mellitus and Mild Cardiac Disease
NCT00521742, Phase 3, Completed, Takeda
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Pioglitazone Compared to Glyburide in Treating Subjects With Type 2 Diabetes Mellitus and Mild Cardiac Disease. Trials, record NCT00521742. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00521742
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Pioglitazone Compared to Glyburide in Treating Subjects With Type 2 Diabetes Mellitus and Mild Cardiac Disease
- NCT number
- NCT00521742
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 300 participants, actual
- Lead sponsor
- Takeda
- Conditions
- Diabetes Mellitus
- Interventions
- Pioglitazone, Glyburide, Pioglitazone, Glyburide
- First posted
- 2007-08-28
- Last updated
- 2012-02-28
Source ClinicalTrials.gov
Registered outcomes11
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in the walking distance during a standardized 6-minute walk test. | Weeks 2, 16, 24, 40, and 52 or Final Visit | |
| Secondary | Morbidity and Mortality Due to Cardiovascular Events. | At occurrence or Weeks 2, 4, 6, 8, 12, 16, 24, 32, 36, 40, 48, and 52 or Final Visit | |
| Secondary | Change in Cardiovascular Treatment Program. | At occurrence or Weeks 2, 4, 6, 8, 12, 16, 24, 32, 36, 40, 48, and 52 or Final Visit | |
| Secondary | Change from Baseline in 12-lead Electrocardiogram Parameter (Ventricular Heart Rate) | Weeks 24 and 52 or Final Visit | |
| Secondary | Change from Baseline in Electrocardiogram Parameter (Left Ventricular Mass) | Week 52 or Final Visit | |
| Secondary | Change from Baseline in Electrocardiogram Parameter (Left Ventricular Ejection Fraction) | Week 52 or Final Visit | |
| Secondary | Change from Baseline in Electrocardiogram Parameter (Cardiac Index) | Week 52 or Final Visit | |
| Secondary | Change from Baseline in Electrocardiogram Parameter (Fractional Shortening) | Week 52 or Final Visit | |
| Secondary | Change in Blood Pressure | Weeks 2, 4, 6, 8, 12, 16, 24, 32, 40, 48, and 52 or Final Visit | |
| Secondary | Change in Heart Rate | Weeks 24 and 52 or Final Visit |
1 to 10 of 11Source ClinicalTrials.gov
See all 11 registered outcomesOutcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 20557330 | RESULT |
Source PubMed
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00521742
GET https://conductscience.org/api/trials/v1/NCT00521742/registered