Trial · NCT00531518
Early Detection and Intervention for the Prevention of Psychosis
NCT00531518, Not applicable, Completed, MaineHealth; results first posted 2016-08-15
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Detection and Intervention for the Prevention of Psychosis. Trials, record NCT00531518. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00531518
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Detection and Intervention for the Prevention of Psychosis
- NCT number
- NCT00531518
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 292 participants, actual
- Lead sponsor
- MaineHealth
- Conditions
- Schizophrenia, Bipolar Disorder, Depression, Psychotic Disorders
- Interventions
- aripiprazole; fluoxetine; bupropion; sertraline; lamotrigine, Psychoeducational multifamily group treatment, Supported employment and education
- First posted
- 2007-09-19
- Last updated
- 2016-08-15
- Results first posted
- 2016-08-15
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Psychotic Symptoms | two years | Psychotic symptoms were assessed and scored using the Structured Interview for the Prodromal Syndrome (SIPS) and the Scale of Prodromal Symptoms (SOPS). The SOPS provides a measure of four domains of symptoms, including positive, negative, disorganized and general symptoms. The Positive Symptom sub-scale score reported is the sum of all five symptom items in the Positive Symptom sub-scale. The Positive Symptom sub-scale assesses psychotic symptoms, each item on a scale of 0-6. The sum scale score is 0-30, with 30 indicating severe psychotic symptoms, while 0 indicates no psychotic symptoms. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Psychotic Symptoms | two years | units on a scale | MEAN |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Psychotic Symptoms | Control | 9.2 | Standard Deviation 1.0 | units on a scale | |
| Psychotic Symptoms | Family-aided Assertive Community Treatment | 6.7 | Standard Deviation 0.4 | units on a scale |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Control Group | 87 | |
| Overall Study | STARTED | Family-aided Assertive Community Treatment | 205 | |
| Overall Study | COMPLETED | Control Group | 55 | |
| Overall Study | COMPLETED | Family-aided Assertive Community Treatment | 134 | |
| Overall Study | NOT COMPLETED | Control Group | 32 | |
| Overall Study | NOT COMPLETED | Family-aided Assertive Community Treatment | 71 |
Source ClinicalTrials.gov
Adverse events4
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Negative events | Psychiatric disorders | Control Group | 19 | 87 | 19 |
| other | Negative events | Psychiatric disorders | Family-aided Assertive Community Treatment | 51 | 205 | 51 |
| serious | suicide | Psychiatric disorders | Control Group | 1 | 87 | 1 |
| serious | suicide | Psychiatric disorders | Family-aided Assertive Community Treatment | 0 | 205 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Control Group | ||
| Total, all-cause mortality | Family-aided Assertive Community Treatment | ||
| Total, other adverse events | Control Group | 19 | 87 |
| Total, other adverse events | Family-aided Assertive Community Treatment | 51 | 205 |
| Total, serious adverse events | Control Group | 1 | 87 |
| Total, serious adverse events | Family-aided Assertive Community Treatment | 0 | 205 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Family-aided Assertive Community Treatment vs Control Group: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00531518
GET https://conductscience.org/api/trials/v1/NCT00531518/registered