Trial · NCT00534404

A Randomized Trial of Internet Access to Nicotine Patches

NCT00534404, Not applicable, Completed, University of Michigan; results first posted 2015-02-03

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. A Randomized Trial of Internet Access to Nicotine Patches. Trials, record NCT00534404. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00534404

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: A Randomized Trial of Internet Access to Nicotine Patches
NCT number: NCT00534404
Status: Completed
Phases: Not applicable
Enrollment: 2,485 participants, actual
Lead sponsor: University of Michigan
Conditions: Smoking Cessation, Tobacco Use Disorder
Interventions: Nicotine patches, Telephone counseling, iQuit Smoking website
First posted: 2007-09-24
Last updated: 2015-02-03
Results first posted: 2015-02-03

Source ClinicalTrials.gov

Registered outcomes3

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Self-reported 6-month Prolonged Abstinence From Smoking	Measured at 9 Months post-randomization	Participants complete the final study survey 9 months following enrollment in the program. They are asked to report when they had last smoked a cigarette, even a puff. Participants who report that they have not smoked in the past 6 months are counted as abstinent for the purposes of our study analysis.
Secondary	Self-reported 30-day Prolonged Abstinence at 9-month Follow up	9 months post randomization
Secondary	Self-reported 30-day Prolonged Abstinence at 3-month Follow up	3-months post randomization

Source ClinicalTrials.gov

Outcomes3

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Self-reported 6-month Prolonged Abstinence From Smoking	Measured at 9 Months post-randomization	All currently enrolled participants were invited via email to complete an online follow-up survey. Participants who did not respond to the email received phone calls from study staff asking them to complete the survey online. Results to this outcome measure are from those subjects who completed the survey.	participants	NUMBER
SECONDARY	Self-reported 30-day Prolonged Abstinence at 9-month Follow up	9 months post randomization		participants	NUMBER
SECONDARY	Self-reported 30-day Prolonged Abstinence at 3-month Follow up	3-months post randomization		participants	NUMBER

Source ClinicalTrials.gov

Results by group9

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Value	Units
Self-reported 6-month Prolonged Abstinence From Smoking	NRT Patch, Phone Counseling, Internet	252	participants
Self-reported 6-month Prolonged Abstinence From Smoking	Nicotine Patches and Internet	194	participants
Self-reported 6-month Prolonged Abstinence From Smoking	Internet	109	participants
Self-reported 30-day Prolonged Abstinence at 9-month Follow up	NRT Patch, Phone Counseling, Internet	310	participants
Self-reported 30-day Prolonged Abstinence at 9-month Follow up	Nicotine Patches and Internet	268	participants
Self-reported 30-day Prolonged Abstinence at 9-month Follow up	Internet	176	participants
Self-reported 30-day Prolonged Abstinence at 3-month Follow up	NRT Patch, Phone Counseling, Internet	379	participants
Self-reported 30-day Prolonged Abstinence at 3-month Follow up	Nicotine Patches and Internet	299	participants
Self-reported 30-day Prolonged Abstinence at 3-month Follow up	Internet	138	participants

Source ClinicalTrials.gov

Participant flow27

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	NRT Patch, Phone Counseling, Internet	827
Overall Study	STARTED	Nicotine Patches and Internet	830
Overall Study	STARTED	Internet	828
Overall Study	Completed at Least 1 Online Session	NRT Patch, Phone Counseling, Internet	781
Overall Study	Completed at Least 1 Online Session	Nicotine Patches and Internet	813
Overall Study	Completed at Least 1 Online Session	Internet	658
Overall Study	Completed First NRT Order	NRT Patch, Phone Counseling, Internet	765
Overall Study	Completed First NRT Order	Nicotine Patches and Internet	821
Overall Study	Completed First NRT Order	Internet	0
Overall Study	Completed Second NRT Order	NRT Patch, Phone Counseling, Internet	640

1 to 10 of 27Source ClinicalTrials.gov

See all 27 participant flow

Adverse events9

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
serious	Death	General disorders	NRT Patch, Phone Counseling, Internet	0	827	0
serious	Death	General disorders	Nicotine Patches and Internet	0	830	0
serious	Death	General disorders	Internet	2	828	2
serious	Hospitalization	Cardiac disorders	NRT Patch, Phone Counseling, Internet	2	827	2
serious	Hospitalization	Cardiac disorders	Nicotine Patches and Internet	0	830	0
serious	Hospitalization	Cardiac disorders	Internet	0	828	0
serious	Chest pain	General disorders	NRT Patch, Phone Counseling, Internet	1	827	1
serious	Chest pain	General disorders	Nicotine Patches and Internet	0	830	0
serious	Chest pain	General disorders	Internet	0	828	0

Source ClinicalTrials.gov

Adverse event totals9

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	NRT Patch, Phone Counseling, Internet
Total, all-cause mortality	Nicotine Patches and Internet
Total, all-cause mortality	Internet
Total, other adverse events	NRT Patch, Phone Counseling, Internet	0	827
Total, other adverse events	Nicotine Patches and Internet	0	830
Total, other adverse events	Internet	0	828
Total, serious adverse events	NRT Patch, Phone Counseling, Internet	3	827
Total, serious adverse events	Nicotine Patches and Internet	0	830
Total, serious adverse events	Internet	2	828

Source ClinicalTrials.gov

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants1

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

Project	Title	Principal investigators	Organization	Funder	Fiscal years
R01HL086684	A Randomized Trial of Internet Access to Nicotine Patches	AN, LAWRENCE CHIN-I	UNIVERSITY OF MICHIGAN AT ANN ARBOR	NATIONAL HEART, LUNG, AND BLOOD INSTITUTE	2007 to 2012

Source NIH RePORTER

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00534404

GET https://conductscience.org/api/trials/v1/NCT00534404/flow?page=2

API reference For AI assistants