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Trial · NCT00537680

Results by group36

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 24Mid Dose Idebenone-2.5Standard Deviation 6.3ICARS points
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 24High Dose Idebenone-2.4Standard Deviation 4.8ICARS points
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 24Placebo-1.3Standard Deviation 4.4ICARS points
Change in Friedreich's Ataxia Rating Scale (FARS) Scores From Baseline to Week 24Mid Dose Idebenone-1.6Standard Deviation 6.52FARS score
Change in Friedreich's Ataxia Rating Scale (FARS) Scores From Baseline to Week 24High Dose Idebenone-1.2Standard Deviation 4.53FARS score
Change in Friedreich's Ataxia Rating Scale (FARS) Scores From Baseline to Week 24Placebo0.6Standard Deviation 5.91FARS score
Activities of Daily Living (ADL) of Friedreich's Ataxia Rating Scale (FARS), Change in ADL (Total Score ) From Baseline to Week 24Mid Dose Idebenone0.2Standard Deviation 2.45ADL points
Activities of Daily Living (ADL) of Friedreich's Ataxia Rating Scale (FARS), Change in ADL (Total Score ) From Baseline to Week 24High Dose Idebenone0.6Standard Deviation 3.13ADL points
Activities of Daily Living (ADL) of Friedreich's Ataxia Rating Scale (FARS), Change in ADL (Total Score ) From Baseline to Week 24Placebo1.0Standard Deviation 2.97ADL points
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 12Mid Dose Idebenone-1.5Standard Deviation 5.35ICARS points
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 12High Dose Idebenone-1.6Standard Deviation 5.53ICARS points
Change in the International Cooperative Ataxia Rating Scale (ICARS) From Baseline Assessment to Week 12Placebo-3.0Standard Deviation 3.52ICARS points
Absolute Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentricleMid Dose Idebenone-0.032Standard Deviation 0.096cm
Absolute Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentricleHigh Dose Idebenone0.007Standard Deviation 0.071cm
Absolute Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentriclePlacebo0.010Standard Deviation 0.097cm
Percent Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentricleMid Dose Idebenone-3.32Standard Deviation 15.300% change
Percent Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentricleHigh Dose Idebenone1.53Standard Deviation 12.560% change
Percent Change From Baseline to Week 24 in the Relative Wall Thickness (RWT) of the Left VentriclePlacebo2.65Standard Deviation 17.135% change
Absolute Change From Baseline to Week 24 in Left Ventricular Mass Index (LVMI)Mid Dose Idebenone-3.06Standard Deviation 6.23g/m2
Absolute Change From Baseline to Week 24 in Left Ventricular Mass Index (LVMI)High Dose Idebenone-2.56Standard Deviation 4.27g/m2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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