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Trial · NCT00540436

Results by group27

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Mean Change From Baseline in Six Minutes Walk Distance (6MWD) at Week 12GSK1325760A33.49Standard Deviation 43.236Meters
Mean Change From Baseline in Six Minutes Walk Distance (6MWD) at Week 24/WithdrawalGSK1325760A46.82Standard Deviation 52.705Meters
Mean Change From Baseline in the Borg Dyspnea Index (BDI) at Weeks 12 and 24GSK1325760AWeek 12-0.60Standard Deviation 2.157Points on a scale
Mean Change From Baseline in the Borg Dyspnea Index (BDI) at Weeks 12 and 24GSK1325760AWeek 24-0.69Standard Deviation 1.904Points on a scale
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760AImproved at Week 129Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760ANo change at Week 1216Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760ADeteriorated at Week 120Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760AImproved at Week 2410Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760ANo change at Week 2414Participants
Number of Participants With a Change From Baseline in Their World Health Organization (WHO) Functional Classification (FC) at Weeks 12 and 24GSK1325760ADeteriorated at Week 241Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) at Week 24, Assessed as the First Occurrence of a Particular Event
GSK1325760ADeath0Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) at Week 24, Assessed as the First Occurrence of a Particular Event
GSK1325760ALung transplantation0Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) at Week 24, Assessed as the First Occurrence of a Particular Event
GSK1325760AHospitalization for PAH treatment0Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) at Week 24, Assessed as the First Occurrence of a Particular Event
GSK1325760AAtrial Septostomy0Participants
Number of Participants With the Indicated Event, as an Assessment of Time to Clinical Worsening of Pulmonary Arterial Hypertension (PAH) at Week 24, Assessed as the First Occurrence of a Particular Event
GSK1325760AStudy discontinuation (additional medication)1Participants
Mean Change From Baseline in Mean Pulmonary Atery Pressure (mPAP) and Mean Right Atrial Pressure (mRAP) at Weeks 12 and 24GSK1325760AmPAP (mmHg) at Week 12, n=21-6.29Standard Deviation 11.201mmHg
Mean Change From Baseline in Mean Pulmonary Atery Pressure (mPAP) and Mean Right Atrial Pressure (mRAP) at Weeks 12 and 24GSK1325760AmRAP (mmHg) at Week 12, n=21-1.12Standard Deviation 3.761mmHg
Mean Change From Baseline in Mean Pulmonary Atery Pressure (mPAP) and Mean Right Atrial Pressure (mRAP) at Weeks 12 and 24GSK1325760AmPAP (mmHg) at Week 24, n=16-8.69Standard Deviation 13.903mmHg
Mean Change From Baseline in Mean Pulmonary Atery Pressure (mPAP) and Mean Right Atrial Pressure (mRAP) at Weeks 12 and 24GSK1325760AmRAP (mmHg) at Week 24, n=16-0.69Standard Deviation 3.683mmHg
Mean Change From Baseline in Cardiac Index (CI) at Weeks 12 and 24GSK1325760AWeek 12, n=210.623Standard Deviation 0.5980L/min/m2

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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