Trial · NCT00548197
Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
NCT00548197, Phase 1, Completed, Iran University of Medical Sciences; results first posted 2018-10-16
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment. Trials, record NCT00548197. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00548197
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Preoperative Injection of Bevacizumab Prior to Vitreoretinal Surgery in Diabetic Tractional Retinal Detachment
- NCT number
- NCT00548197
- Status
- Completed
- Phases
- Phase 1
- Enrollment
- 40 participants, actual
- Lead sponsor
- Iran University of Medical Sciences
- Conditions
- Intravitreal Bevacizumab Injection, Pars Plana Vitrectomy, Tractional Retinal Detachment, Diabetic Retinopathy
- Interventions
- Bevacizumab
- First posted
- 2007-10-23
- Last updated
- 2018-10-16
- Results first posted
- 2018-10-16
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Best Corrected Visual Acuity | last follow up, an average of 7 months post-operation | Post operative best corrected visual acuity ( best distance vision with eyeglasses or contact lenses) |
| Secondary | Anatomic Status of the Retina | Last follow up, an average of 7 months post-operation | Number of Participants with Postoperative Vitreous Hemorrhage |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Best Corrected Visual Acuity | last follow up, an average of 7 months post-operation | LogMar | MEAN | |
| SECONDARY | Anatomic Status of the Retina | Last follow up, an average of 7 months post-operation | Postoperative Vitreous Hemorrhage | Participants | COUNT_OF_PARTICIPANTS |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Best Corrected Visual Acuity | Intervention | 1.1 | Standard Deviation 0.4 | LogMar | |
| Best Corrected Visual Acuity | Control | 1.4 | Standard Deviation 0.3 | LogMar | |
| Anatomic Status of the Retina | Intervention Group | 0 | Participants | ||
| Anatomic Status of the Retina | Control Group | 7 | Participants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Control Group | 18 | |
| Overall Study | STARTED | Intervention Group | 22 | |
| Overall Study | COMPLETED | Control Group | 18 | |
| Overall Study | COMPLETED | Intervention Group | 22 | |
| Overall Study | NOT COMPLETED | Control Group | 0 | |
| Overall Study | NOT COMPLETED | Intervention Group | 0 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Inferior rhegmatogenous retinal detachment and perisillicone proliferations | Eye disorders | Intervention | 1 | 22 | 1 |
| serious | Inferior rhegmatogenous retinal detachment and perisillicone proliferations | Eye disorders | Control | 1 | 18 | 1 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Intervention | 0 | 22 |
| Total, all-cause mortality | Control | 0 | 18 |
| Total, other adverse events | Intervention | 0 | 22 |
| Total, other adverse events | Control | 0 | 18 |
| Total, serious adverse events | Intervention | 1 | 22 |
| Total, serious adverse events | Control | 1 | 18 |
Source ClinicalTrials.gov
Papers3
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons3
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Intervention Group vs Control Group: Anatomic Status of the Retina | Trial comparisons |
| Intervention vs Control: deaths from any cause | Trial comparisons |
| Intervention vs Control: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00548197
GET https://conductscience.org/api/trials/v1/NCT00548197/registered