Trial · NCT00552513
Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
NCT00552513, Not applicable, Completed, Population Health Research Institute; results first posted 2014-06-27
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes. Trials, record NCT00552513. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00552513
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Early Versus Delayed Timing of Intervention in Patients With Acute Coronary Syndromes
- NCT number
- NCT00552513
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 3,031 participants, actual
- Lead sponsor
- Population Health Research Institute
- Conditions
- Unstable Angina, Myocardial Infarction
- Interventions
- Early Coronary Intervention, Delayed Coronary Intervention
- First posted
- 2007-11-02
- Last updated
- 2022-04-21
- Other registries' IDs
- isrctn:ISRCTN20993046
- Results first posted
- 2014-06-27
Source ClinicalTrials.gov
Registered outcomes6
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Composite of Death, Myocardial (re-) Infarction, or Stroke | 180 days | |
| Secondary | First Occurrence of Any Component of the Composite of Death, MI, or Refractory Ischemia | 180 days | |
| Secondary | Composite of Death, MI, Stroke, Refractory Ischemia or Repeat Revascularization at 180 Days | 180 days | |
| Secondary | Stroke at 30 Days and 180 Days | 180 days | |
| Secondary | Need for Mechanical or Pharmacological Coronary Revascularization (i.e. Thrombolysis, PCI, CABG) at Days 30, 90, and 180 | 180 days | |
| Secondary | In-hospital Major Bleeding | Hospital discharge |
Source ClinicalTrials.gov
Outcomes6
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Composite of Death, Myocardial (re-) Infarction, or Stroke | 180 days | All patients were included in the final intention-to-treat analysis. Event rates in the two groups were estimated with the use of the Kaplan-Meier method. The hazard ratio and two-sided 95% confidence intervals were calculated with the use of a Cox proportional-hazards model. | participants | NUMBER |
| SECONDARY | First Occurrence of Any Component of the Composite of Death, MI, or Refractory Ischemia | 180 days | participants | NUMBER | |
| SECONDARY | Composite of Death, MI, Stroke, Refractory Ischemia or Repeat Revascularization at 180 Days | 180 days | Eparticipants | NUMBER | |
| SECONDARY | Stroke at 30 Days and 180 Days | 180 days | |||
| SECONDARY | Need for Mechanical or Pharmacological Coronary Revascularization (i.e. Thrombolysis, PCI, CABG) at Days 30, 90, and 180 | 180 days | |||
| SECONDARY | In-hospital Major Bleeding | Hospital discharge |
Source ClinicalTrials.gov
Results by group6
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Composite of Death, Myocardial (re-) Infarction, or Stroke | Early Intervention | 153 | 0.68 to 1.06 | participants | |
| Composite of Death, Myocardial (re-) Infarction, or Stroke | Delayed Intervention | 163 | 0.68 to 1.06 | participants | |
| First Occurrence of Any Component of the Composite of Death, MI, or Refractory Ischemia | Early Intervention | 151 | participants | ||
| First Occurrence of Any Component of the Composite of Death, MI, or Refractory Ischemia | Delayed Intervention | 186 | participants | ||
| Composite of Death, MI, Stroke, Refractory Ischemia or Repeat Revascularization at 180 Days | Early Intervention | 264 | Eparticipants | ||
| Composite of Death, MI, Stroke, Refractory Ischemia or Repeat Revascularization at 180 Days | Delayed Intervention | 280 | Eparticipants |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Early | 1,593 | |
| Overall Study | STARTED | Delayed | 1,438 | |
| Overall Study | COMPLETED | Early | 1,588 | |
| Overall Study | COMPLETED | Delayed | 1,437 | |
| Overall Study | NOT COMPLETED | Early | 5 | |
| Overall Study | NOT COMPLETED | Delayed | 1 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Early | ||
| Total, all-cause mortality | Delayed | ||
| Total, other adverse events | Early | 0 | 0 |
| Total, other adverse events | Delayed | 0 | 0 |
| Total, serious adverse events | Early | 0 | 0 |
| Total, serious adverse events | Delayed | 0 | 0 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Early Intervention vs Delayed Intervention: First Occurrence of Any Component of the Composite of Death, MI, or Refractory Ischemia | Trial comparisons |
| Early Intervention vs Delayed Intervention: Composite of Death, Myocardial (re-) Infarction, or Stroke | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00552513
GET https://conductscience.org/api/trials/v1/NCT00552513/registered