Trial · NCT00574067
Buprenorphine for Prisoners
NCT00574067, Phase 3, Completed, Friends Research Institute, Inc.; results first posted 2016-04-11
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Buprenorphine for Prisoners. Trials, record NCT00574067. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00574067
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Buprenorphine for Prisoners
- NCT number
- NCT00574067
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 213 participants, actual
- Lead sponsor
- Friends Research Institute, Inc.
- Conditions
- Heroin Addiction
- Interventions
- Buprenorphine +OTP, Buprenorphine +CHC, Counseling +OTP, Counseling +CHC
- First posted
- 2007-12-14
- Last updated
- 2018-08-29
- Results first posted
- 2016-04-11
Source ClinicalTrials.gov
Registered outcomes7
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Days of Heroin Use | 1 year | mean days used heroin during the past 30 days |
| Primary | Drug Abuse Treatment Entry and Retention in the Community | 1 year | entered community treatment within 10 days of release from prison (yes vs. no) |
| Secondary | Number of Days of Cocaine Use | 1 year | Number of days used cocaine during the past 30 days. |
| Secondary | Criminal Activity | 1 year | Days of crime during the past 30 days |
| Secondary | Employment Status | 1 year | Number of days employed during the past year |
| Secondary | HIV Risk Behavior Needle Sharing | 1 year | Number of times shared a needle during the past year |
| Secondary | HIV Risk Behavior | 1 year | Number of times had sex without using a condom during the past year |
Source ClinicalTrials.gov
Outcomes7
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Days of Heroin Use | 1 year | days | MEAN | |
| PRIMARY | Drug Abuse Treatment Entry and Retention in the Community | 1 year | participants | NUMBER | |
| SECONDARY | Number of Days of Cocaine Use | 1 year | days | MEAN | |
| SECONDARY | Criminal Activity | 1 year | days | MEAN | |
| SECONDARY | Employment Status | 1 year | days | MEAN | |
| SECONDARY | HIV Risk Behavior Needle Sharing | 1 year | times | MEAN | |
| SECONDARY | HIV Risk Behavior | 1 year | times | MEAN |
Source ClinicalTrials.gov
Results by group28
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Days of Heroin Use | Bup+OTP | 6.0 | Standard Deviation 11.4 | days | |
| Number of Days of Heroin Use | Bup+CHC | 6.4 | Standard Deviation 11.5 | days | |
| Number of Days of Heroin Use | Counseling+OTP | 6.5 | Standard Deviation 11.3 | days | |
| Number of Days of Heroin Use | Counseling+CHC | 4.0 | Standard Deviation 9.0 | days | |
| Drug Abuse Treatment Entry and Retention in the Community | B+OTP | 22 | participants | ||
| Drug Abuse Treatment Entry and Retention in the Community | B+CHC | 26 | participants | ||
| Drug Abuse Treatment Entry and Retention in the Community | C+OTP | 23 | participants | ||
| Drug Abuse Treatment Entry and Retention in the Community | C+CHC | 11 | participants | ||
| Number of Days of Cocaine Use | Bup+OTP | 1.1 | Standard Deviation 4.3 | days | |
| Number of Days of Cocaine Use | Bup+CHC | 4.1 | Standard Deviation 9.5 | days |
1 to 10 of 28Source ClinicalTrials.gov
See all 28 results by groupParticipant flow12
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Bup+OTP | 53 | |
| Overall Study | STARTED | Bup+CHC | 53 | |
| Overall Study | STARTED | Counseling+OTP | 54 | |
| Overall Study | STARTED | Counseling+CHC | 53 | |
| Overall Study | COMPLETED | Bup+OTP | 52 | |
| Overall Study | COMPLETED | Bup+CHC | 52 | |
| Overall Study | COMPLETED | Counseling+OTP | 54 | |
| Overall Study | COMPLETED | Counseling+CHC | 53 | |
| Overall Study | NOT COMPLETED | Bup+OTP | 1 | |
| Overall Study | NOT COMPLETED | Bup+CHC | 1 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 participant flowAdverse events104
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | constipation | Gastrointestinal disorders | B+OTP | 1 | 52 | 1 |
| serious | constipation | Gastrointestinal disorders | B+CHC | 0 | 0 | 0 |
| serious | constipation | Gastrointestinal disorders | C+OTP | 0 | 54 | 0 |
| serious | constipation | Gastrointestinal disorders | C+CHC | 0 | 53 | 0 |
| serious | back injury | Injury, poisoning and procedural complications | B+OTP | 1 | 52 | 1 |
| serious | back injury | Injury, poisoning and procedural complications | B+CHC | 0 | 52 | 0 |
| serious | back injury | Injury, poisoning and procedural complications | C+OTP | 0 | 54 | 0 |
| serious | back injury | Injury, poisoning and procedural complications | C+CHC | 0 | 53 | 0 |
| serious | swollen foot | Investigations | B+OTP | 1 | 52 | 1 |
| serious | swollen foot | Investigations | B+CHC | 0 | 52 | 0 |
1 to 10 of 104Source ClinicalTrials.gov
See all 104 adverse eventsAdverse event totals12
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | B+OTP | ||
| Total, all-cause mortality | B+CHC | ||
| Total, all-cause mortality | C+OTP | ||
| Total, all-cause mortality | C+CHC | ||
| Total, other adverse events | B+OTP | 0 | 0 |
| Total, other adverse events | B+CHC | 0 | 0 |
| Total, other adverse events | C+OTP | 0 | 0 |
| Total, other adverse events | C+CHC | 0 | 0 |
| Total, serious adverse events | B+OTP | 4 | 52 |
| Total, serious adverse events | B+CHC | 14 | 52 |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 adverse event totalsPapers3
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| R01DA021579 | Buprenorphine for Prisoners | KINLOCK, TIMOTHY W | FRIENDS RESEARCH INSTITUTE, INC. | NATIONAL INSTITUTE ON DRUG ABUSE | 2007 to 2011 |
Source NIH RePORTER
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00574067
GET https://conductscience.org/api/trials/v1/NCT00574067/results?page=2