Trial · NCT00585104
Myocardial Hemodynamic Effects of Levosimendan
NCT00585104, Phase 2, Completed, University of Utah; results first posted 2010-06-09
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Myocardial Hemodynamic Effects of Levosimendan. Trials, record NCT00585104. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00585104
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Myocardial Hemodynamic Effects of Levosimendan
- NCT number
- NCT00585104
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 10 participants, actual
- Lead sponsor
- University of Utah
- Conditions
- Heart Failure
- Interventions
- levosimendan
- First posted
- 2008-01-03
- Last updated
- 2013-05-21
- Results first posted
- 2010-06-09
- Limitations and caveats
- Of the ten (10) patients enrolled, only 6 patients completed the study protocol for which we collected data. The data is insufficient to provide a formal summary for publication.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Left Ventricular End-diastolic Pressure (LVEDP) Using Pressure-volume Catheter. | From baseline to 30-minutes after levosimendan started. | Left ventricular end-diastolic pressure (LVEDP) recorded from CD Leycom ConductNT software analysis. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Left Ventricular End-diastolic Pressure (LVEDP) Using Pressure-volume Catheter. | From baseline to 30-minutes after levosimendan started. | Ten patients were enrolled. Complete data was available in 6 patients. The primary endpoint was change in left ventricular end diastolic pressure (LVEDP) from baseline to 30-minutes after starting levosimendan. An Intent to Treat (ITT) analysis was performed. | mmHg | MEAN |
Source ClinicalTrials.gov
Results by group1
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Left Ventricular End-diastolic Pressure (LVEDP) Using Pressure-volume Catheter. | Levosimendan, Compare Heart Function and Metabolism | 5.67 | Standard Deviation 4.32 | mmHg |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Levosimendan, Compare Heart Function and Metabolism | 10 | |
| Overall Study | COMPLETED | Levosimendan, Compare Heart Function and Metabolism | 6 | |
| Overall Study | NOT COMPLETED | Levosimendan, Compare Heart Function and Metabolism | 4 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Levosimendan, Compare Heart Function and Metabolism | ||
| Total, other adverse events | Levosimendan, Compare Heart Function and Metabolism | 0 | 10 |
| Total, serious adverse events | Levosimendan, Compare Heart Function and Metabolism | 0 | 10 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00585104
GET https://conductscience.org/api/trials/v1/NCT00585104/registered