Trial · NCT00587054
Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders
NCT00587054, Phase 2, Completed, Memorial Sloan Kettering Cancer Center; results first posted 2017-03-10
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders. Trials, record NCT00587054. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00587054
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
Trial of Allogeneic Stem Cell Transplants From HLA Compatible, Related and Unrelated Donors After a Myeloablative Preparative Regimen With Hyperfractionated TBI, Thiotepa and Fludarabine For Adult Patients With Lymphohematopoietic Disorders
- NCT number
- NCT00587054
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 129 participants, actual
- Lead sponsor
- Memorial Sloan Kettering Cancer Center
- Conditions
- Allogeneic Stem Cell Transplant, Leukemia, Non-Hodgkins, Lymphoblastic Lymphoma, Myelodysplastic Syndrome, Paroxysmal Nocturnal Hemoglobinuria (PNH)
- Interventions
- cytoreductive regimen followed by a CD34+E- selected allogeneic stem cell transplant
- First posted
- 2008-01-07
- Last updated
- 2017-03-10
- Results first posted
- 2017-03-10
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Overall Survival of Transplant Patients | up to 6 years | Calculate the median overall survival of transplant patients |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Overall Survival of Transplant Patients | up to 6 years | Days | MEDIAN |
Source ClinicalTrials.gov
Results by group1
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Overall Survival of Transplant Patients | Transplant Patients | 727.5 | Full Range 12 to 2231 | Days |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Transplant Patients | 129 | |
| Overall Study | COMPLETED | Transplant Patients | 120 | |
| Overall Study | NOT COMPLETED | Transplant Patients | 9 |
Source ClinicalTrials.gov
Adverse events30
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Alkaline phosphatase | Metabolism and nutrition disorders | Transplant Patients | 23 | 129 | 23 |
| other | Bilirubin | Metabolism and nutrition disorders | Transplant Patients | 31 | 129 | 31 |
| other | Creatinine | Metabolism and nutrition disorders | Transplant Patients | 13 | 129 | 13 |
| other | Hemoglobin (Hgb) | Blood and lymphatic system disorders | Transplant Patients | 117 | 129 | 117 |
| other | Hyperglycemia | Metabolism and nutrition disorders | Transplant Patients | 58 | 129 | 58 |
| other | Hyperkalemia | Metabolism and nutrition disorders | Transplant Patients | 26 | 129 | 26 |
| other | Hypocalcemia | Metabolism and nutrition disorders | Transplant Patients | 35 | 129 | 35 |
| other | Hypokalemia | Metabolism and nutrition disorders | Transplant Patients | 60 | 129 | 60 |
| other | Hyponatremia | Metabolism and nutrition disorders | Transplant Patients | 35 | 129 | 35 |
| other | Hypophosphatemia | Metabolism and nutrition disorders | Transplant Patients | 48 | 129 | 48 |
1 to 10 of 30Source ClinicalTrials.gov
See all 30 adverse eventsAdverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Transplant Patients | ||
| Total, other adverse events | Transplant Patients | 126 | 129 |
| Total, serious adverse events | Transplant Patients | 13 | 129 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00587054
GET https://conductscience.org/api/trials/v1/NCT00587054/events?page=2