Trial · NCT00598429
Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure
NCT00598429, Phase 2, Withdrawn, NICHD Neonatal Research Network
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure. Trials, record NCT00598429. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00598429
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure
- NCT number
- NCT00598429
- Status
- Withdrawn
- Phases
- Phase 2
- Enrollment
- 0 participants, actual
- Lead sponsor
- NICHD Neonatal Research Network
- Conditions
- Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn, Streptococcal Infections
- Interventions
- Inhaled Prostaglandin E1
- First posted
- 2008-01-21
- Last updated
- 2019-03-22
Source ClinicalTrials.gov
Registered outcomes10
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The ability to recruit an adequate number of patients (n = 50) in a 6-9 month period without excessive (>20%) protocol violations. | 6-9 months after trial begins recruitment | |
| Secondary | Progression to an OI greater than 25 | 72-hours after enrollment | |
| Secondary | Improvement in partial pressure of oxygen (PaO2) in the blood gas | 72-hours after enrollment | |
| Secondary | Change in OI | 72 hours after enrollment | |
| Secondary | Death | 72-hours after intervention | |
| Secondary | Need for inhaled nitric oxide or ECMO | 72-hours after enrollment | |
| Secondary | Length of hospitalization | ||
| Secondary | Duration of mechanical ventilation | ||
| Secondary | Number of days of oxygen used and need for supplemental oxygen at 28 days of life | ||
| Secondary | Occurrence of grade III-IV intracranial hemorrhage and cystic leukomalacia |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers1
The papers the trial lists on ClinicalTrials.gov.
| PMID | Listed as |
|---|---|
| 25496504 | DERIVED |
Source PubMed
Grants11
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years | Source |
|---|---|---|---|---|---|---|
| U10HD036790 | Neonatal Research Network Data Coordinating Center (DCC) | DAS, ABHIK | RESEARCH TRIANGLE INSTITUTE | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2008 to 2017 | NIH RePORTER |
| U10HD021364 | Multicenter Network of Neonatal Intensive Care Units | WALSH, MICHELE | CASE WESTERN RESERVE UNIVERSITY | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 1991 to 2015 | NIH RePORTER |
| U10HD021385 | Cooperative Multicenter Network of Neontal Intensive Care Units | SHANKARAN, SEETHA | WAYNE STATE UNIVERSITY | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 1991 to 2015 | NIH RePORTER |
| U10HD027880 | NICHD Cooperative Multicenter Neonatal Research Network | VAN MEURS, KRISA PAGE | STANFORD UNIVERSITY | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 1991 to 2015 | NIH RePORTER |
| U10HD034216 | Cooperative Multicenter Neonatal Research Network - UAB | CARLO FONT, WALDEMAR A. | UNIVERSITY OF ALABAMA AT BIRMINGHAM | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 1996 to 2015 | NIH RePORTER |
| U10HD040492 | Eunice Kennedy Shriver NICHD Cooperative Multicenter Neonatal Research Network | COTTEN, CHARLES MICHAEL | DUKE UNIVERSITY | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2001 to 2015 | NIH RePORTER |
| U10HD040689 | NICHD Cooperative Multicenter Neonatal Research Network | WYCKOFF, MYRA HELEN | UT SOUTHWESTERN MEDICAL CENTER | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2001 to 2015 | NIH RePORTER |
| U10HD053089 | NICHD Cooperative Multicenter Neonatal Research Network | WATTERBERG, KRISTI L. | UNIVERSITY OF NEW MEXICO | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2006 to 2015 | NIH RePORTER |
| U10HD053109 | NICHD Cooperative Multicenter Neonatal Research Network | BELL, EDWARD F | UNIVERSITY OF IOWA | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2006 to 2015 | NIH RePORTER |
| U10HD053119 | NICHD Cooperative Multicenter Neonatal Research Network | DAMMANN, CHRISTIANE E | TUFTS MEDICAL CENTER | EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT | 2006 to 2015 | NIH RePORTER |
1 to 10 of 11
See all 11 grantsTrial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00598429
GET https://conductscience.org/api/trials/v1/NCT00598429/registered