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Trial · NCT00607477

Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension

NCT00607477, Not applicable, Terminated, University of Chicago; results first posted 2011-02-16

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension. Trials, record NCT00607477. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00607477

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Pilot Study of the Treatment of Vascular Endothelial Growth Factor(VEGF)Signaling Pathway Inhibitor-Induced Hypertension
NCT number
NCT00607477
Status
Terminated
Phases
Not applicable
Enrollment
2 participants, actual
Lead sponsor
University of Chicago
Conditions
Treatment Induced Hypertension
Interventions
Minoxidil, Hydralazine
First posted
2008-02-05
Last updated
2014-06-10
Results first posted
2011-02-16
Limitations and caveats
This study enrolled only 2 subjects and due to poor accrual, enrollment was stopped early. Due to the limited number of subjects available results cannot be assessed.

Source ClinicalTrials.gov

Registered outcomes1

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryMagnitude of Change in Blood Pressure21 days

Outcomes1

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

TypeOutcomeTime framePopulationUnitsMeasured as
PRIMARYMagnitude of Change in Blood Pressure21 daysNo participants analyzed due to poor accrual and insufficient numbers of participants.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow6

How many started, completed or left each group, period by period.

PeriodMilestoneGroupParticipantsUnits counted
Overall StudySTARTEDHydralazine0
Overall StudySTARTEDMinoxidil2
Overall StudyCOMPLETEDHydralazine0
Overall StudyCOMPLETEDMinoxidil2
Overall StudyNOT COMPLETEDHydralazine0
Overall StudyNOT COMPLETEDMinoxidil0

Adverse events2

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

TypeEventOrgan systemGroupAffectedAt riskEvents
otherdiarrhea (grade 1)Gastrointestinal disordersHydralazine000
otherdiarrhea (grade 1)Gastrointestinal disordersMinoxidil121

Adverse event totals6

The totals the trial posted for each group.

TotalGroupAffectedAt risk
Total, all-cause mortalityHydralazine
Total, all-cause mortalityMinoxidil
Total, other adverse eventsHydralazine00
Total, other adverse eventsMinoxidil12
Total, serious adverse eventsHydralazine00
Total, serious adverse eventsMinoxidil02

Papers0

The papers the trial lists on ClinicalTrials.gov.

None in this release.

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00607477

GET https://conductscience.org/api/trials/v1/NCT00607477/registered