Trial · NCT00612352
Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
NCT00612352, Not applicable, Completed, Yale University; results first posted 2017-02-24
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism. Trials, record NCT00612352. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00612352
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
- NCT number
- NCT00612352
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 180 participants, actual
- Lead sponsor
- Yale University
- Conditions
- Alcoholism
- Interventions
- Ethanol High Dose, Ethanol Low Dose, and Placebo
- First posted
- 2008-02-11
- Last updated
- 2021-10-26
- Results first posted
- 2017-02-24
Source ClinicalTrials.gov
Registered outcomes55
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Number of Drinks Felt Consumed at Baseline | Baseline | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 10 Minutes | 10 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 30 Minutes | 30 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 110 Minutes | 110 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 140 Minutes | 140 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 170 Minutes | 170 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Number of Drinks Felt Consumed at 230 Minutes | 230 minutes | The Number of Drinks Scale asks Subjects to report on the number of alcoholic drinks they felt they had consumed. |
| Primary | Visual Analog Scale of Similarity to Alcohol - Baseline | Baseline | Visual Analog Scale of Similarity to Alcohol data using the Likert scale (0 Not at all similar to alcohol - 7 Extremely similar to alcohol) evaluating the similarity of drug effects to alcohol |
| Primary | Visual Analog Scale of Similarity to Alcohol -10 Minutes | 10 minutes | Visual Analog Scale of Similarity to Alcohol data using the Likert scale (0 Not at all similar to alcohol - 7 Extremely similar to alcohol) evaluating the similarity of drug effects to alcohol |
| Primary | Visual Analog Scale of Similarity to Alcohol - 30 Minutes | 30 minutes | Visual Analog Scale of Similarity to Alcohol data using the Likert scale (0 Not at all similar to alcohol - 7 Extremely similar to alcohol) evaluating the similarity of drug effects to alcohol |
1 to 10 of 55Source ClinicalTrials.gov
See all 55 registered outcomesOutcomes55
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Number of Drinks Felt Consumed at Baseline | Baseline | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 10 Minutes | 10 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 30 Minutes | 30 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 110 Minutes | 110 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 140 Minutes | 140 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 170 Minutes | 170 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Number of Drinks Felt Consumed at 230 Minutes | 230 minutes | All available data was utilized in the analysis using mixed models. | drinks felt consumed | MEAN |
| PRIMARY | Visual Analog Scale of Similarity to Alcohol - Baseline | Baseline | All available data was utilized in the analysis using mixed models. | units on a scale | MEAN |
| PRIMARY | Visual Analog Scale of Similarity to Alcohol -10 Minutes | 10 minutes | All available data was utilized in the analysis using mixed models. | units on a scale | MEAN |
| PRIMARY | Visual Analog Scale of Similarity to Alcohol - 30 Minutes | 30 minutes | All available data was utilized in the analysis using mixed models. | units on a scale | MEAN |
1 to 10 of 55Source ClinicalTrials.gov
See all 55 outcomesResults by group330
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Number of Drinks Felt Consumed at Baseline | Family History Positive | Placebo | 0 | Standard Deviation 0 | drinks felt consumed |
| Number of Drinks Felt Consumed at Baseline | Family History Negative | Placebo | 0 | Standard Deviation 0 | drinks felt consumed |
| Number of Drinks Felt Consumed at Baseline | Family History Positive | Alcohol 40mg% | 0 | Standard Deviation 0 | drinks felt consumed |
| Number of Drinks Felt Consumed at Baseline | Family History Negative | Alcohol 40mg% | 0 | Standard Deviation 0 | drinks felt consumed |
| Number of Drinks Felt Consumed at Baseline | Family History Positive | Alcohol 100mg% | 0 | Standard Deviation 0 | drinks felt consumed |
| Number of Drinks Felt Consumed at Baseline | Family History Negative | Alcohol 100mg% | 0.04 | Standard Deviation 0.23 | drinks felt consumed |
| Number of Drinks Felt Consumed at 10 Minutes | Family History Positive | Placebo | 0.07 | Standard Deviation 0.42 | drinks felt consumed |
| Number of Drinks Felt Consumed at 10 Minutes | Family History Negative | Placebo | 0.08 | Standard Deviation 0.37 | drinks felt consumed |
| Number of Drinks Felt Consumed at 10 Minutes | Family History Positive | Alcohol 40mg% | 0.49 | Standard Deviation 0.8 | drinks felt consumed |
| Number of Drinks Felt Consumed at 10 Minutes | Family History Negative | Alcohol 40mg% | 0.7 | Standard Deviation 0.92 | drinks felt consumed |
1 to 10 of 330Source ClinicalTrials.gov
See all 330 results by groupParticipant flow16
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Family History Positive | 65 | |
| Overall Study | STARTED | Family History Negative | 115 | |
| Overall Study | 40%mg & 100%mg | Family History Positive | 1 | |
| Overall Study | 40%mg & 100%mg | Family History Negative | 1 | |
| Overall Study | Placebo & 100%mg | Family History Positive | 1 | |
| Overall Study | Placebo & 100%mg | Family History Negative | 0 | |
| Overall Study | 100%mg | Family History Positive | 2 | |
| Overall Study | 100%mg | Family History Negative | 1 | |
| Overall Study | 40%mg | Family History Positive | 1 | |
| Overall Study | 40%mg | Family History Negative | 0 |
1 to 10 of 16Source ClinicalTrials.gov
See all 16 participant flowAdverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | vomiting | Gastrointestinal disorders | Family History Positive | 1 | 65 | 1 |
| other | vomiting | Gastrointestinal disorders | Family History Negative | 0 | 115 | 0 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Family History Positive | ||
| Total, all-cause mortality | Family History Negative | ||
| Total, other adverse events | Family History Positive | 1 | 65 |
| Total, other adverse events | Family History Negative | 0 | 115 |
| Total, serious adverse events | Family History Positive | 0 | 65 |
| Total, serious adverse events | Family History Negative | 0 | 115 |
Source ClinicalTrials.gov
Papers2
The papers the trial lists on ClinicalTrials.gov.
Grants1
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
| Project | Title | Principal investigators | Organization | Funder | Fiscal years |
|---|---|---|---|---|---|
| P50AA012870 | Center for the Translational Neuroscience of Alcohol | Krystal, John H. | YALE UNIVERSITY | NATIONAL INSTITUTE ON ALCOHOL ABUSE AND ALCOHOLISM | 2001 to 2026 |
Source NIH RePORTER
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Family History Positive vs Family History Negative: serious adverse events |
Source Trial comparisons
Tests1
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
| Test | Named as |
|---|---|
| Verbal Learning | Secondary outcome |
Source ConductCognition
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00612352
GET https://conductscience.org/api/trials/v1/NCT00612352/registered?page=2