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Trial · NCT00613626

Results by group32

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Time to Disease Progression - Median Time to Progression and Log-Rank TestArm A: ZD6474 Matched Placebo5.6895% Confidence Interval 3.98 to 6.41Months
Time to Disease Progression - Median Time to Progression and Log-Rank TestArm B: ZD64745.6295% Confidence Interval 5.09 to 6.24Months
Percentage of Participants With Grade 3/4 Hematologic and Non-Hematologic ToxicitiesArm A: ZD6474 Matched PlaceboGrade 3/4 Hematologic Toxicity11.00percentage of participants
Percentage of Participants With Grade 3/4 Hematologic and Non-Hematologic ToxicitiesArm B: ZD6474 + Safety Lead-InGrade 3/4 Hematologic Toxicity13.75percentage of participants
Percentage of Participants With Grade 3/4 Hematologic and Non-Hematologic ToxicitiesArm A: ZD6474 Matched PlaceboGrade 3/4 Non-Hematologic Toxicity2.71percentage of participants
Percentage of Participants With Grade 3/4 Hematologic and Non-Hematologic ToxicitiesArm B: ZD6474 + Safety Lead-InGrade 3/4 Non-Hematologic Toxicity4.30percentage of participants
Measure the Response Rate (CR + PR) in Each ArmArm A: ZD6474 Matched Placebo65.3895% Confidence Interval 47.10 to 83.67percentage of participants
Measure the Response Rate (CR + PR) in Each ArmArm B: ZD647450.0095% Confidence Interval 31.48 to 68.52percentage of participants
Measure Disease Control Rate (CR + PR+ SD) in Each ArmArm A: ZD6474 Matched Placebo73.0895% Confidence Interval 56.03 to 90.13percentage of participants
Measure Disease Control Rate (CR + PR+ SD) in Each ArmArm B: ZD647475.0095% Confidence Interval 58.96 to 91.04percentage of participants
Measure Overall Survival for Each ArmArm A: ZD6474 Matched Placebo9.2395% Confidence Interval 6.64 to 11.27Months
Measure Overall Survival for Each ArmArm B: ZD647413.2495% Confidence Interval 7.82 to 17.38Months
Assess VEGF Polymorphisms and Correlate Subject ResponseArm A: ZD6474 Matched PlaceboSurvival Analysis VEGF SNP rs6999470.4642probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm B: ZD6474Survival Analysis VEGF SNP rs6999470.6148probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm A: ZD6474 Matched PlaceboSurvival Analysis VEGF SNP rs30250390.1234probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm B: ZD6474Survival Analysis VEGF SNP rs30250390.2050probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm A: ZD6474 Matched PlaceboSurvival Analysis VEGF SNP rs20190630.3968probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm B: ZD6474Survival Analysis VEGF SNP rs20190630.8486probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm A: ZD6474 Matched PlaceboSurvival Analysis VEGF SNP rs15703600.0712probability
Assess VEGF Polymorphisms and Correlate Subject ResponseArm B: ZD6474Survival Analysis VEGF SNP rs15703600.4426probability

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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