Trial · NCT00617175
Avoid DeliVering TherApies for Non-sustained Arrhythmias in ICD PatiEnts III
NCT00617175, Phase 4, Completed, Medtronic Cardiac Rhythm and Heart Failure; results first posted 2013-02-25
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Avoid DeliVering TherApies for Non-sustained Arrhythmias in ICD PatiEnts III. Trials, record NCT00617175. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00617175
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Avoid DeliVering TherApies for Non-sustained Arrhythmias in ICD PatiEnts III
- NCT number
- NCT00617175
- Status
- Completed
- Phases
- Phase 4
- Enrollment
- 1,902 participants, actual
- Lead sponsor
- Medtronic Cardiac Rhythm and Heart Failure
- Conditions
- Heart Disease
- Interventions
- Implantable Defibrillator, Implantable Defibrillator
- First posted
- 2008-02-15
- Last updated
- 2025-07-02
- Results first posted
- 2013-02-25
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | For the Primary Endpoint the Reduction of Ventricular Therapies (ATP and Shocks) Delivered for Treating Fast Spontaneous Arrhythmia Episodes Was Measured. | From enrollment to study completion or exit whichever occured first | for each patient, the exposure time was calculated as the period between randomization and until study completion or exit whichever occured first. Exposure times for all patients were then summed. The rate of therapies was calculated as the sum of all therapies delivered in the study (for each arm) over the sum of exposure times \* 100. |
| Secondary | Evaluate the Percent Reduction in the Number of Shocks Delivered Per Subject for Treating Spontaneous Episodes With a Fast Cycle Length (CL < 320 ms) and for Spontaneous Ventricular Episodes. | end of study |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | For the Primary Endpoint the Reduction of Ventricular Therapies (ATP and Shocks) Delivered for Treating Fast Spontaneous Arrhythmia Episodes Was Measured. | From enrollment to study completion or exit whichever occured first | For the primary endpoint analysis, only patients with at least a device data record were considered. | rate of therapies per 100 patient-years | NUMBER |
| SECONDARY | Evaluate the Percent Reduction in the Number of Shocks Delivered Per Subject for Treating Spontaneous Episodes With a Fast Cycle Length (CL < 320 ms) and for Spontaneous Ventricular Episodes. | end of study |
Source ClinicalTrials.gov
Results by group2
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| For the Primary Endpoint the Reduction of Ventricular Therapies (ATP and Shocks) Delivered for Treating Fast Spontaneous Arrhythmia Episodes Was Measured. | NID 18/24 | 67.1 | 95% Confidence Interval 61.7 to 72.9 | rate of therapies per 100 patient-years | |
| For the Primary Endpoint the Reduction of Ventricular Therapies (ATP and Shocks) Delivered for Treating Fast Spontaneous Arrhythmia Episodes Was Measured. | NID 30/40 | 41.9 | 95% Confidence Interval 27.6 to 46.5 | rate of therapies per 100 patient-years |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Short NID | 954 | |
| Overall Study | STARTED | Long NID | 948 | |
| Overall Study | COMPLETED | Short NID | 954 | |
| Overall Study | COMPLETED | Long NID | 948 | |
| Overall Study | NOT COMPLETED | Short NID | 0 | |
| Overall Study | NOT COMPLETED | Long NID | 0 |
Source ClinicalTrials.gov
Adverse events60
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| serious | Thromboembolic Events | Blood and lymphatic system disorders | Short NID | 16 | 954 | |
| serious | Thromboembolic Events | Blood and lymphatic system disorders | Long NID | 8 | 948 | |
| serious | Lead Dislodgment | Cardiac disorders | Short NID | 27 | 954 | |
| serious | Lead Dislodgment | Cardiac disorders | Long NID | 20 | 948 | |
| serious | Worsening heart failure | Cardiac disorders | Short NID | 95 | 954 | |
| serious | Worsening heart failure | Cardiac disorders | Long NID | 83 | 948 | |
| serious | System Dysfunction | Cardiac disorders | Short NID | 1 | 954 | |
| serious | System Dysfunction | Cardiac disorders | Long NID | 1 | 948 | |
| serious | Inappropriate Tachyarrhythmia Therapy | Cardiac disorders | Short NID | 7 | 954 | |
| serious | Inappropriate Tachyarrhythmia Therapy | Cardiac disorders | Long NID | 5 | 948 |
1 to 10 of 60Source ClinicalTrials.gov
See all 60 adverse eventsAdverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Short NID | ||
| Total, all-cause mortality | Long NID | ||
| Total, other adverse events | Short NID | 0 | 954 |
| Total, other adverse events | Long NID | 0 | 948 |
| Total, serious adverse events | Short NID | 300 | 954 |
| Total, serious adverse events | Long NID | 258 | 948 |
Source ClinicalTrials.gov
Papers7
The papers the trial lists on ClinicalTrials.gov.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons1
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison |
|---|
| Short NID vs Long NID: serious adverse events |
Source Trial comparisons
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00617175
GET https://conductscience.org/api/trials/v1/NCT00617175/events?page=2