Trial · NCT00667225
Efficacy of Cantharidin in Molluscum Contagiosum
NCT00667225, Not applicable, Completed, University of North Carolina, Chapel Hill; results first posted 2011-06-01
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy of Cantharidin in Molluscum Contagiosum. Trials, record NCT00667225. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00667225
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy of Cantharidin in Molluscum Contagiosum
- NCT number
- NCT00667225
- Status
- Completed
- Phases
- Not applicable
- Enrollment
- 29 participants, actual
- Lead sponsor
- University of North Carolina, Chapel Hill
- Conditions
- Molluscum Contagiosum, Skin Disease
- Interventions
- cantharidin's vehicle, Cantharidin 0.7%
- First posted
- 2008-04-28
- Last updated
- 2011-06-21
- Results first posted
- 2011-06-01
- Limitations and caveats
Small sample size and random disproportionate assignment to the vehicle group. Other limitations include short duration of follow up and interval between treatments. Finally, matching subjects in each group with comparable lesion counts.
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Patients Experiencing Complete Clearance of All Molluscum Lesions. | Baseline compared to 8 weeks (5 visits) | |
| Secondary | Mean Change in Each Group Measured by Lesion Count. | Baseline compared to 8 weeks (5 visits) | Average change in number of lesions from baseline to 8 weeks |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Patients Experiencing Complete Clearance of All Molluscum Lesions. | Baseline compared to 8 weeks (5 visits) | We used a power calculation to estimate the number of patients needed to detect a clinically significant result. | Participants | NUMBER |
| SECONDARY | Mean Change in Each Group Measured by Lesion Count. | Baseline compared to 8 weeks (5 visits) | lesions | MEAN |
Source ClinicalTrials.gov
Results by group4
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Patients Experiencing Complete Clearance of All Molluscum Lesions. | Vehicle | 1 | Participants | ||
| Patients Experiencing Complete Clearance of All Molluscum Lesions. | Cantharidin | 3 | Participants | ||
| Mean Change in Each Group Measured by Lesion Count. | Vehicle | 26.26 | Standard Deviation 27.55 | lesions | |
| Mean Change in Each Group Measured by Lesion Count. | Cantharidin | 35.61 | Standard Deviation 48.15 | lesions |
Source ClinicalTrials.gov
Participant flow6
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Vehicle | 16 | |
| Overall Study | STARTED | Cantharidin | 13 | |
| Overall Study | COMPLETED | Vehicle | 15 | |
| Overall Study | COMPLETED | Cantharidin | 12 | |
| Overall Study | NOT COMPLETED | Vehicle | 1 | |
| Overall Study | NOT COMPLETED | Cantharidin | 1 |
Source ClinicalTrials.gov
Adverse events2
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Pain after application of cantharidin or vehicle | Skin and subcutaneous tissue disorders | Vehicle | 1 | 16 | 1 |
| other | Pain after application of cantharidin or vehicle | Skin and subcutaneous tissue disorders | Cantharidin | 3 | 13 | 3 |
Source ClinicalTrials.gov
Adverse event totals6
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Vehicle | ||
| Total, all-cause mortality | Cantharidin | ||
| Total, other adverse events | Vehicle | 1 | 16 |
| Total, other adverse events | Cantharidin | 3 | 13 |
| Total, serious adverse events | Vehicle | 0 | 16 |
| Total, serious adverse events | Cantharidin | 0 | 13 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons2
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
| Comparison | Source |
|---|---|
| Cantharidin vs Vehicle: Patients Experiencing Complete Clearance of All Molluscum Lesions. | Trial comparisons |
| Cantharidin vs Vehicle: serious adverse events | Trial comparisons |
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00667225
GET https://conductscience.org/api/trials/v1/NCT00667225/registered