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Trial · NCT00669773

Validate Gene Expression and Proteomic Signatures Predictive of Treatment for Response for Breast Cancer Patient

NCT00669773, Phase 2, Unknown, National University Hospital, Singapore

3 sourcestrials-2026-11-12-0.5.0

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ConductScience Library. Validate Gene Expression and Proteomic Signatures Predictive of Treatment for Response for Breast Cancer Patient. Trials, record NCT00669773. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00669773

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Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title
Validate Gene Expression and Proteomic Signatures Predictive of Treatment for Response for Breast Cancer Patient
NCT number
NCT00669773
Status
Unknown
Phases
Phase 2
Enrollment
49 participants, actual
Lead sponsor
National University Hospital, Singapore
Conditions
Breast Cancer
Interventions
Adriamycin, Docetaxel
First posted
2008-04-30
Last updated
2013-12-10

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

ListOutcomeTime frameDescription
PrimaryClinical and pathological response rate12 weeksClinical and pathological response rate to four cycles of pre-operative chemotherapy.
SecondaryBaseline and serial changes in tumor & plasma genomic and proteomic changesat different time-points (see description below)
Core biopsy of breast tumor before treatment, after one cycle of pre-operative chemotherapy, and after the fourth cycle of pre-operative chemotherapy or study withdrawal for a total of 3 core biopsies. Plasma samples for proteomics before treatment, during pre-operative chemotherapy and before surgery, before first cycle of post-operative chemotherapy, within 4 weeks after completion of 4 cycles of post-operative chemotherapy, and four monthly thereafter.

Outcomes0

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

None in this release.

Results by group0

Each measurement the trial posted, group by group, in the words and numbers it posted.

None in this release.

Participant flow0

How many started, completed or left each group, period by period.

None in this release.

Adverse events0

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

None in this release.

Adverse event totals0

The totals the trial posted for each group.

None in this release.

Papers3

The papers the trial lists on ClinicalTrials.gov.

PMIDListed asSource
11867112BACKGROUNDPubMed
15718313BACKGROUNDPubMed
23116553DERIVEDPubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons0

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

None in this release.

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov
2026-11-12
ClinicalTrials.gov
Results, from AACT
2026-03-23
AACT
NIH grant links
2026-11-13
NIH RePORTER

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00669773

GET https://conductscience.org/api/trials/v1/NCT00669773/registered