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Trial · NCT00679354

Results by group14

Each measurement the trial posted, group by group, in the words and numbers it posted.

OutcomeGroupCategoryValueSpreadUnits
Objective Response to CilengitideTreatment (Cilengitide)With Objective Response1participants
Objective Response to CilengitideTreatment (Cilengitide)Without Objective Response23participants
Time to Tumor Progression (TTP)Treatment (Cilengitide)28Inter-Quartile Range 25 to 41Days
Time to Treatment Failure (TTF)Treatment (Cilengitide)28Inter-Quartile Range 25 to 41Days
Time to Death (TTD)Treatment (Cilengitide)172Inter-Quartile Range 99 to 226Days
Rate of Toxicity, Especially That of Symptomatic Intratumoral Hemorrhage (ITH) Assessed by Common Terminology Criteria for Adverse Events Version 4.0Treatment (Cilengitide)6.9percent of pts with symptomatic ITH
Pharmacokinetic Parameter of Cilengitide in Plasma: Volume of Central Compartment (Vc)Treatment (Cilengitide)6.20Full Range 3.34 to 10.72L/m^2
Pharmacokinetic Parameter of Cilengitide in Plasma: Elimination Rate Constant (Ke)Treatment (Cilengitide)0.58Full Range 0.36 to 1.00hr^(-1)
Pharmacokinetic Parameter of Cilengitide in Plasma: Half-life (t1/2)Treatment (Cilengitide)1.26Full Range 0.69 to 1.90hours
Pharmacokinetic Parameter of Cilengitide in Plasma: Systemic Clearance (Cl)Treatment (Cilengitide)3.84Full Range 2.47 to 5.75L/hr/m^2
Pharmacogenetic Polymorphism in Drug Transporter Gene ABCB1 and Relate to Cilengitide Disposition as Measured by AUCTreatment (Cilengitide)0.00Spearman's correlation
Pharmacogenetic Polymorphism in Drug Transporter Gene ABCB1 and Relate to Cilengitide Disposition as Measured by Systemic ClearanceTreatment (Cilengitide)0.56Spearman's Correlation
Pharmacogenetic Polymorphism in Drug Transporter Gene ABCG2 and Relate to Cilengitide Disposition as Measured by AUCTreatment (Cilengitide)-0.22Spearman's Correlation
Pharmacogenetic Polymorphism in Drug Transporter Gene ABCG2 and Relate to Cilengitide Disposition as Measured by Systemic ClearanceTreatment (Cilengitide)-0.48Spearman's Correlation

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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