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Efficacy and Safety of Oral Salmon Calcitonin in Patients With Knee Osteoarthritis (OA 2 Study)
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Trial · NCT00704847

Results by group40

Each measurement the trial posted, group by group, in the words and numbers it posted.

1 to 20 of 40

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OutcomeGroupCategoryValueSpreadUnits
Joint Space Width (JSW) in the Medial Tibia-femoral Knee Joint in the Signal Knee Measured by X-ray Change From Baseline Over 24 MonthsSMC021 Oral Calcitonin-0.32Standard Deviation 0.693mm
Joint Space Width (JSW) in the Medial Tibia-femoral Knee Joint in the Signal Knee Measured by X-ray Change From Baseline Over 24 MonthsSMC021 Placebo-0.40Standard Deviation 0.768mm
Pain Subscore Change From Baseline Over 24 Months as Assessed by Western Ontario and McMaster Universities Arthritis (WOMAC) IndexSMC021 Oral Calcitonin-80.6Standard Deviation 112.22Units on a scale
Pain Subscore Change From Baseline Over 24 Months as Assessed by Western Ontario and McMaster Universities Arthritis (WOMAC) IndexSMC021 Placebo-87.9Standard Deviation 116.25Units on a scale
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Oral CalcitoninSerum CTX-I (ng/mL)50.6Standard Deviation 83.74percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 PlaceboSerum CTX-I (ng/mL)40.6Standard Deviation 45.52percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Oral CalcitoninSerum Osteocalcin (ng/mL)3.6Standard Deviation 37.42percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 PlaceboSerum Osteocalcin (ng/mL)3.9Standard Deviation 26.32percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Oral Calcitonin24-h urine CTX-I/creatinine (µg/mmol)9.8Standard Deviation 85.95percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Placebo24-h urine CTX-I/creatinine (µg/mmol)7.2Standard Deviation 44.36percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Oral Calcitonin24-h urine CTX-II/creatinine (ng/mmol)2.6Standard Deviation 63.13percentage of change
Bone & Cartilage Metabolism Biochemical Marker Change (Percentage).SMC021 Placebo24-h urine CTX-II/creatinine (ng/mmol)2.3Standard Deviation 51.07percentage of change
Knee Disease Progression Assessed by MRISMC021 Oral CalcitoninCartilage Volume Month 123.4Standard Deviation 9.11percentage of change
Knee Disease Progression Assessed by MRISMC021 PlaceboCartilage Volume Month 123.0Standard Deviation 13.16percentage of change
Knee Disease Progression Assessed by MRISMC021 Oral CalcitoninCartilage Volume Month 242.6Standard Deviation 10.18percentage of change
Knee Disease Progression Assessed by MRISMC021 PlaceboCartilage Volume Month 243.5Standard Deviation 12.73percentage of change
Knee Disease Progression Assessed by MRISMC021 Oral CalcitoninCartilage Thickness Month 124.7Standard Deviation 10.64percentage of change
Knee Disease Progression Assessed by MRISMC021 PlaceboCartilage Thickness Month 124.7Standard Deviation 8.24percentage of change
Knee Disease Progression Assessed by MRISMC021 Oral CalcitoninCartilage Thickness Month 244.5Standard Deviation 10.78percentage of change
Knee Disease Progression Assessed by MRISMC021 PlaceboCartilage Thickness Month 244.1Standard Deviation 8.67percentage of change

Source ClinicalTrials.govtrials-2026-11-12-0.5.0

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Sources 3

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ClinicalTrials.govNo license stated
  • NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ClinicalTrials.govnone stated
  • NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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