Trial · NCT00720122
Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
NCT00720122, Phase 2, Completed, Massachusetts General Hospital; results first posted 2012-02-29
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa. Trials, record NCT00720122. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00720122
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Effects of rhIGF-1 on Bone Metabolism in Adolescent Girls With Anorexia Nervosa
- NCT number
- NCT00720122
- Status
- Completed
- Phases
- Phase 2
- Enrollment
- 28 participants, actual
- Lead sponsor
- Massachusetts General Hospital
- Conditions
- Disorder of Bone Density and Structure, Unspecified
- Interventions
- Recombinant human insulin like growth factor-1 (rhIGF-1)
- First posted
- 2008-07-22
- Last updated
- 2021-11-18
- Results first posted
- 2012-02-29
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change in Spine Bone Density (g/cm^2) | Baseline and 6 months | Change in spine bone density over 6 months (6month data- baseline data). Bone density at the spine was assessed using dual energy x-ray absorptiometry at baseline and 6 months and the change in bone density over these 6 months was calculated. |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change in Spine Bone Density (g/cm^2) | Baseline and 6 months | The study participants analyzed were those that completed the first 6 months of the study and had a bone density performed at the baseline visit and then again at the 6 month visit as per protocol. | gm/cm^2 | MEAN |
Source ClinicalTrials.gov
Results by group1
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Change in Spine Bone Density (g/cm^2) | Anorexia Nervosa Females | -0.00558 | Standard Error 0.00653 | gm/cm^2 |
Source ClinicalTrials.gov
Participant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Anorexia Nervosa Females | 28 | |
| Overall Study | COMPLETED | Anorexia Nervosa Females | 19 | |
| Overall Study | NOT COMPLETED | Anorexia Nervosa Females | 9 |
Source ClinicalTrials.gov
Adverse events45
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
| Type | Event | Organ system | Group | Affected | At risk | Events |
|---|---|---|---|---|---|---|
| other | Itchiness at Injection Site | General disorders | Anorexia Nervosa Females | 4 | 28 | 6 |
| other | Facial Discoloration | General disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Diarrhea | Gastrointestinal disorders | Anorexia Nervosa Females | 2 | 28 | 2 |
| other | Fall | General disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Food Poisoning | Gastrointestinal disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Elevated Aspartate Aminotransferase | General disorders | Anorexia Nervosa Females | 4 | 28 | 9 |
| other | Severe Weight Loss | General disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Vomiting | Gastrointestinal disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Femoral Lymph Node Enlargement | General disorders | Anorexia Nervosa Females | 1 | 28 | 1 |
| other | Bruising | General disorders | Anorexia Nervosa Females | 4 | 28 | 4 |
1 to 10 of 45Source ClinicalTrials.gov
See all 45 adverse eventsAdverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Anorexia Nervosa Females | ||
| Total, other adverse events | Anorexia Nervosa Females | 22 | 28 |
| Total, serious adverse events | Anorexia Nervosa Females | 5 | 28 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00720122
GET https://conductscience.org/api/trials/v1/NCT00720122/events?page=2