Trial · NCT00726544
Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy
NCT00726544, Phase 2, Terminated, Archemix Corp.
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy. Trials, record NCT00726544. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00726544
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Clinical Outcome Study of ARC1779 Injection in Patients With Thrombotic Microangiopathy
- NCT number
- NCT00726544
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 100 participants, estimated
- Lead sponsor
- Archemix Corp.
- Conditions
- Thrombotic Microangiopathy, Thrombotic Thrombocytopenic Purpura
- Interventions
- ARC 1779 Placebo, ARC1779 Injection, ARC1779 Injection, ARC1779 Injection
- First posted
- 2008-08-01
- Last updated
- 2009-11-26
Source ClinicalTrials.gov
Registered outcomes5
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The incidence of the clinical composite of death (all-cause mortality), stroke, coma, seizures, renal failure, or acute myocardial infarction (AMI) | 6 weeks post randomization | |
| Secondary | Neurocognitive function is to be assessed with the CogState® test system. | Once during the hospitalization period and again at the 6 week clinic visit. | |
| Secondary | The incidence of death, stroke, or acute renal failure/injury requiring dialysis is to be assessed. | During the extended clinical follow-up for each patient from the time of the 6 week clinic visit until the study is closed. | |
| Secondary | Safety- and efficacy-related clinical laboratory parameters and biomarkers will be analyzed in relation to ARC1779 exposure in terms of the dose administered and the observed plasma concentration. | During initial hospitalization and at 6 week clinic visit. | |
| Secondary | The incidence of the composite of complications associated with plasma exchange therapy (i.e., catheter-related infection, thrombosis, internal hemorrhage, or pneumothorax) is to be assessed. | During initial hospitalization and at the 6 week clinic visit. |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00726544
GET https://conductscience.org/api/trials/v1/NCT00726544/registered