Trial · NCT00735267
A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD)
NCT00735267, Phase 3, Terminated, Pfizer
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD). Trials, record NCT00735267. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00735267
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- A 52-Week Open-Label Safety Study of PD 0332334 in Subjects With Generalized Anxiety Disorder (GAD)
- NCT number
- NCT00735267
- Status
- Terminated
- Phases
- Phase 3
- Enrollment
- 468 participants, actual
- Lead sponsor
- Pfizer
- Conditions
- Generalized Anxiety Disorder
- Interventions
- PD 0332334
- First posted
- 2008-08-14
- Last updated
- 2012-11-16
Source ClinicalTrials.gov
Registered outcomes8
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | The nature, incidence, and duration of adverse events monitored throughout the study by physical exam | Screening, Wk 25 & Wk 52/EOT | |
| Primary | Electrocardiogram will be performed at screening and during follow up visits to assess the safety and tolerability of the compound in terms of clinically significant cardiovascular changes | Screening, Wk 4, Wk 25, Wk 52/EOT | |
| Primary | The Columbia Suicide Severity Rating scale will be used to assess any suicide related adverse events | As needed | |
| Primary | The nature, incidence, and duration of adverse events monitored throughout the study by vital signs evaluation at each visit, weight measurements and clinical laboratory monitoring periodically | Screening, Baseline, Wk 4, Wk 12, Wk 25, Wk 38, & Wk 52/EOT | |
| Primary | All discontinuations due to adverse events will be reviewed throughout the trial to assess the safety and tolerability of the compound | Weekly | |
| Secondary | The Hamilton Rating Scale for Anxiety (HAM-A) will be used to assess symptoms of Generalized Anxiety Disorder (GAD) over a one year time period. | Baseline, Wk 12, Wk 25, Wk 38, Wk 51 & Wk 52/EOT | |
| Secondary | The Clinical Global Impression of Severity (CGI-S), and the Daily Diary (DD) will also be used to assess symptoms of GAD over a one year time period. | Baseline, Wk 51 & Wk 52/EOT | |
| Secondary | The Health Care Utilization Questionnaire will be utilized to assess overall Health Care over a one year time period. | Baseline, Wk 12, Wk 25, Wk 38 & Wk 51 |
Source ClinicalTrials.gov
Outcomes0
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
None in this release.
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow0
How many started, completed or left each group, period by period.
None in this release.
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals0
The totals the trial posted for each group.
None in this release.
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00735267
GET https://conductscience.org/api/trials/v1/NCT00735267/registered