Trial · NCT00737594
Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension
NCT00737594, Phase 2, Terminated, Sucampo Pharma Americas, LLC; results first posted 2016-03-16
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension. Trials, record NCT00737594. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00737594
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- Efficacy and Safety of Cobiprostone in Patients With Portal Hypertension
- NCT number
- NCT00737594
- Status
- Terminated
- Phases
- Phase 2
- Enrollment
- 9 participants, actual
- Lead sponsor
- Sucampo Pharma Americas, LLC
- Conditions
- Portal Hypertension
- Interventions
- Placebo, Cobiprostone
- First posted
- 2008-08-19
- Last updated
- 2019-11-18
- Results first posted
- 2016-03-16
- Limitations and caveats
- The trial terminated before data were collected.
Source ClinicalTrials.gov
Registered outcomes1
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Change From Baseline in Hepatic Venous Pressure Gradient (HVPG) After Four (4) Weeks of Treatment | 4 weeks |
Source ClinicalTrials.gov
Outcomes1
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Change From Baseline in Hepatic Venous Pressure Gradient (HVPG) After Four (4) Weeks of Treatment | 4 weeks | Study terminated early, data were not collected. |
Source ClinicalTrials.gov
Results by group0
Each measurement the trial posted, group by group, in the words and numbers it posted.
None in this release.
Participant flow9
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Placebo | 0 | |
| Overall Study | STARTED | 12 mcg TID | 0 | |
| Overall Study | STARTED | 18 mcg TID | 0 | |
| Overall Study | COMPLETED | Placebo | 0 | |
| Overall Study | COMPLETED | 12 mcg TID | 0 | |
| Overall Study | COMPLETED | 18 mcg TID | 0 | |
| Overall Study | NOT COMPLETED | Placebo | 0 | |
| Overall Study | NOT COMPLETED | 12 mcg TID | 0 | |
| Overall Study | NOT COMPLETED | 18 mcg TID | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals9
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Placebo | ||
| Total, all-cause mortality | 12 mcg TID | ||
| Total, all-cause mortality | 18 mcg TID | ||
| Total, other adverse events | Placebo | 0 | 0 |
| Total, other adverse events | 12 mcg TID | 0 | 0 |
| Total, other adverse events | 18 mcg TID | 0 | 0 |
| Total, serious adverse events | Placebo | 0 | 0 |
| Total, serious adverse events | 12 mcg TID | 0 | 0 |
| Total, serious adverse events | 18 mcg TID | 0 | 0 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00737594
GET https://conductscience.org/api/trials/v1/NCT00737594/registered