Trial · NCT00741156
The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
NCT00741156, Phase 3, Completed, The Hospital for Sick Children; results first posted 2015-12-18
3 sourcestrials-2026-11-12-0.5.0
Cite this record
ConductScience Library. The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution. Trials, record NCT00741156. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00741156
On this page
Trial
As registered on ClinicalTrials.gov, in the graph's capture of the registry.
- Title
- The Acute Effects of the Angiotensin-converting Enzyme Inhibitor Enalaprilat on Flow Distribution
- NCT number
- NCT00741156
- Status
- Completed
- Phases
- Phase 3
- Enrollment
- 12 participants, actual
- Lead sponsor
- The Hospital for Sick Children
- Conditions
- Hypertension, Congestive Cardiomyopathy
- Interventions
- Enalaprilat
- First posted
- 2008-08-26
- Last updated
- 2015-12-18
- Results first posted
- 2015-12-18
Source ClinicalTrials.gov
Registered outcomes2
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Baseline and after enalaprilat | |
| Primary | Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Baseline and after enalaprilat | Systemic, pulmonary and cerebral resistance is compared at baseline and after enalaprilat |
Source ClinicalTrials.gov
Outcomes2
Each outcome the trial posted results for, in ClinicalTrials.gov's words.
| Type | Outcome | Time frame | Population | Units | Measured as |
|---|---|---|---|---|---|
| PRIMARY | Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Baseline and after enalaprilat | l/min/m2 | MEDIAN | |
| PRIMARY | Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Baseline and after enalaprilat | Wood units per metre squared | MEDIAN |
Source ClinicalTrials.gov
Results by group12
Each measurement the trial posted, group by group, in the words and numbers it posted.
| Outcome | Group | Category | Value | Spread | Units |
|---|---|---|---|---|---|
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Systemic Blood Flow Baseline | 1.4 | Inter-Quartile Range 0.9 to 1.8 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Systemic Blood Flow After Enalaprilat | 1.8 | Inter-Quartile Range 1.0 to 2.2 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Pulmonary Blood Flow Baseline | 1.9 | Inter-Quartile Range 1.8 to 2.9 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Pulmonary Blood Flow After Enaliprilat | 1.9 | Inter-Quartile Range 1.6 to 2.5 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Cerebral Blood Flow Baseline | 1.9 | Inter-Quartile Range 1.6 to 2.9 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Blood Flow at Baseline and After Enalaprilat | Cerebral Blood Flow After Enalaprilat | 1.8 | Inter-Quartile Range 1.6 to 2.5 | l/min/m2 | |
| Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Systemic Resistance at Baseline | 40.94 | Full Range 26.63 to 67.83 | Wood units per metre squared | |
| Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Systemic Resistance After Enalaprilat | 20.26 | Full Range 16.5 to 28.16 | Wood units per metre squared | |
| Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Pulmonary Resistance at Baseline | 2.87 | Full Range 1.03 to 4.47 | Wood units per metre squared | |
| Systemic, Pulmonary and Cerebral Resistance at Baseline and After Enalaprilat | Pulmonary Resistance After Enalaprilat | 2.54 | Full Range 0.49 to 4.76 | Wood units per metre squared |
1 to 10 of 12Source ClinicalTrials.gov
See all 12 results by groupParticipant flow3
How many started, completed or left each group, period by period.
| Period | Milestone | Group | Participants | Units counted |
|---|---|---|---|---|
| Overall Study | STARTED | Enalaprilat | 12 | |
| Overall Study | COMPLETED | Enalaprilat | 12 | |
| Overall Study | NOT COMPLETED | Enalaprilat | 0 |
Source ClinicalTrials.gov
Adverse events0
Each adverse event the trial posted, group by group: the participants affected out of those at risk.
None in this release.
Adverse event totals3
The totals the trial posted for each group.
| Total | Group | Affected | At risk |
|---|---|---|---|
| Total, all-cause mortality | Enalaprilat | ||
| Total, other adverse events | Enalaprilat | 0 | 12 |
| Total, serious adverse events | Enalaprilat | 0 | 12 |
Source ClinicalTrials.gov
Papers0
The papers the trial lists on ClinicalTrials.gov.
None in this release.
Grants0
The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.
None in this release.
Trial comparisons0
Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.
None in this release.
Tests0
The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.
None in this release.
Data dates
The day each source was copied for this release.
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this trial from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/trials/v1/NCT00741156
GET https://conductscience.org/api/trials/v1/NCT00741156/registered