Trial · NCT00747487
Registered outcomes13
Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.
1 to 13 of 13
Download this page as JSON| List | Outcome | Time frame | Description |
|---|---|---|---|
| Primary | Best recovery of logMAR visual acuity between baseline and Week 24 in either right or left eye | 24 weeks | |
| Secondary | Change in the patient's best logMAR visual acuity between baseline and week 24 | 24 weeks | |
| Secondary | Change in scotoma area in both eyes | Day -1, Week 4, Week 12, Week 24 | |
| Secondary | Change in optic nerve fibre layer thickness in both eyes | Day -1, Week 4, Week 12, Week 24 | |
| Secondary | Colour contrast sensitivity in both eyes (in a subset of patients) | Day -1, Week 4, Week 12, Week 24 | |
| Secondary | logMAR visual acuity as a continuous variable in both eyes | Screening, Day -1, Week 4, Week 12, Week 24, Week 28 | |
| Secondary | Clinical Global Impression of Change | Week 4, Week 12 and Week 24 | |
| Secondary | Change in Health-Related Quality of Life (HRQOL) | Day -1, Week 4, Week 12, Week 24 | |
| Secondary | Change in self-reported general energy levels | Day -1, Week 4, Week 12, Week 24, Week 28 | |
| Secondary | Proportion of patients in which visual acuity in the initially least affected eye does not deteriorate to 1.0 log MAR or more ( in LHON patients with eye still less affected than 0.5 logMAR at trial entry) | 24 weeks | |
| Secondary | Plasma levels of idebenone matched to measures of efficacy and safety | 24 weeks | |
| Secondary | • Best visual acuity at Week 24 (best eye at Week 24) compared to best visual acuity at Baseline (best eye at Baseline) | 24 weeks | |
| Secondary | • Count of eyes/ patients for which the visual acuity improves between baseline and week 24 | 24 weeks |
Source ClinicalTrials.govtrials-2026-11-12-0.5.0
Sources 3
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ClinicalTrials.govNo license stated
- NIH RePORTER's clinical studies and project filesPublic domain
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ClinicalTrials.govnone stated
- NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this list from software.
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GET https://conductscience.org/api/trials/v1/NCT00747487/registered