Trial · NCT00761969

Prevention of Ischemic Events in Patients With Peripheral Arterial Disease

NCT00761969, Completed, KRKA; results first posted 2015-11-17

3 sourcestrials-2026-11-12-0.5.0

Cite this record

ConductScience Library. Prevention of Ischemic Events in Patients With Peripheral Arterial Disease. Trials, record NCT00761969. Release trials-2026-11-12-0.5.0, 12 Nov 2026. https://conductscience.org/library/trials/NCT00761969

On this page

Trial

As registered on ClinicalTrials.gov, in the graph's capture of the registry.

Title: Prevention of Ischemic Events in Patients With Peripheral Arterial Disease
NCT number: NCT00761969
Status: Completed
Enrollment: 1,455 participants, actual
Lead sponsor: KRKA
Conditions: Peripheral Arterial Disease
Interventions: Implementation of the European Guidelines on cardiovascular Disease Prevention in Clinical Practice
First posted: 2008-09-30
Last updated: 2015-11-17
Results first posted: 2015-11-17

Source ClinicalTrials.gov

Registered outcomes2

Each outcome the trial registered, primary first, in ClinicalTrials.gov's words.

List	Outcome	Time frame	Description
Primary	Incidence of Major Cardiovascular Events	5 years:	Total number of deaths, cardiovascular deaths, non-fatal myocardial infarctions, ischemic strokes and critical limb ischemia.
Secondary	Incidence of Revascularization Procedures	5 years	Incidence of coronary, carotid and peripheral arterial revascularization procedures

Source ClinicalTrials.gov

Outcomes2

Each outcome the trial posted results for, in ClinicalTrials.gov's words.

Type	Outcome	Time frame	Population	Units	Measured as
PRIMARY	Incidence of Major Cardiovascular Events	5 years:		participants	NUMBER
SECONDARY	Incidence of Revascularization Procedures	5 years		participants	NUMBER

Source ClinicalTrials.gov

Results by group18

Each measurement the trial posted, group by group, in the words and numbers it posted.

Outcome	Group	Category	Value	Units
Incidence of Major Cardiovascular Events	Peripheral Arterial Disease	Death of all causes	112	participants
Incidence of Major Cardiovascular Events	Control	Death of all causes	47	participants
Incidence of Major Cardiovascular Events	Peripheral Arterial Disease	Cardiovascular death	51	participants
Incidence of Major Cardiovascular Events	Control	Cardiovascular death	17	participants
Incidence of Major Cardiovascular Events	Peripheral Arterial Disease	Non-fatal myocardial infarction	50	participants
Incidence of Major Cardiovascular Events	Control	Non-fatal myocardial infarction	21	participants
Incidence of Major Cardiovascular Events	Peripheral Arterial Disease	Non-fatal ischemic stroke	22	participants
Incidence of Major Cardiovascular Events	Control	Non-fatal ischemic stroke	14	participants
Incidence of Major Cardiovascular Events	Peripheral Arterial Disease	Critical limb ischemia	11	participants
Incidence of Major Cardiovascular Events	Control	Critical limb ischemia	0	participants

1 to 10 of 18Source ClinicalTrials.gov

See all 18 results by group

Participant flow6

How many started, completed or left each group, period by period.

Period	Milestone	Group	Participants
Overall Study	STARTED	Peripheral Arterial Disease	742
Overall Study	STARTED	Control	713
Overall Study	COMPLETED	Peripheral Arterial Disease	542
Overall Study	COMPLETED	Control	573
Overall Study	NOT COMPLETED	Peripheral Arterial Disease	200
Overall Study	NOT COMPLETED	Control	140

Source ClinicalTrials.gov

Adverse events16

Each adverse event the trial posted, group by group: the participants affected out of those at risk.

Type	Event	Organ system	Group	Affected	At risk	Events
other	Peripheral arterial revascularization procedure	Vascular disorders	Peripheral Arterial Disease	183	742	183
other	Peripheral arterial revascularization procedure	Vascular disorders	Control	2	713	2
other	Coronary revascularization procedure	Vascular disorders	Peripheral Arterial Disease	64	742	64
other	Coronary revascularization procedure	Vascular disorders	Control	20	713	20
other	Carotid revascularization	Vascular disorders	Peripheral Arterial Disease	31	742	31
other	Carotid revascularization	Vascular disorders	Control	8	713	8
other	Abdominal aortic revascularization	Vascular disorders	Peripheral Arterial Disease	6	742	6
other	Abdominal aortic revascularization	Vascular disorders	Control	0	713	0
serious	Death of all causes	General disorders	Peripheral Arterial Disease	112	742	112
serious	Death of all causes	General disorders	Control	47	713	47

1 to 10 of 16Source ClinicalTrials.gov

See all 16 adverse events

Adverse event totals6

The totals the trial posted for each group.

Total	Group	Affected	At risk
Total, all-cause mortality	Peripheral Arterial Disease
Total, all-cause mortality	Control
Total, other adverse events	Peripheral Arterial Disease	284	742
Total, other adverse events	Control	30	713
Total, serious adverse events	Peripheral Arterial Disease	195	742
Total, serious adverse events	Control	82	713

Source ClinicalTrials.gov

Papers10

The papers the trial lists on ClinicalTrials.gov.

PMID	Listed as	Source
1729621	BACKGROUND	PubMed
10073955	BACKGROUND	PubMed
10639539	BACKGROUND	PubMed
11560536	BACKGROUND	PubMed
11786451	BACKGROUND	PubMed
12114036	BACKGROUND	PubMed
12964575	BACKGROUND	PubMed
18091132	BACKGROUND	PubMed
22233617	DERIVED	PubMed
27332992	DERIVED	PubMed

Grants0

The grants NIH RePORTER links to the trial, newest funded first: NIH's, and some of AHRQ's, CDC's, FDA's and VA's. Each shows its title, principal investigators, organization and funder in its newest year.

None in this release.

Trial comparisons1

Comparisons of the trial's two groups, calculated by ConductScience from the counts it posted.

Comparison
Peripheral Arterial Disease vs Control: serious adverse events

Source Trial comparisons

Tests0

The ConductCognition tests this trial's registered outcomes name, as ScienceGraph matched them in trial-tests-2026-11-12-0.2.1.

None in this release.

Data dates

The day each source was copied for this release.

ClinicalTrials.gov: 2026-11-12; ClinicalTrials.gov
Results, from AACT: 2026-03-23; AACT
NIH grant links: 2026-11-13; NIH RePORTER

Sources 3

ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
ClinicalTrials.govNo license stated
NIH RePORTER's clinical studies and project filesPublic domain

Each source's terms

ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
ClinicalTrials.govnone stated
NIH RePORTER's clinical studies and project filesPublic domain (NIH RePORTER)

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this trial from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/trials/v1/NCT00761969

GET https://conductscience.org/api/trials/v1/NCT00761969/registered

API reference For AI assistants